The F-loop of the GABA A receptor gamma2 subunit contributes to benzodiazepine modulation.
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Structural mechanisms underlying benzodiazepine modulation of the GABA(A) receptorA residue in loop 9 of the beta2-subunit stabilizes the closed state of the GABAA receptor.Ligand- and subunit-specific conformational changes in the ligand-binding domain and the TM2-TM3 linker of {alpha}1 {beta}2 {gamma}2 GABAA receptorsAllosteric modulators induce distinct movements at the GABA-binding site interface of the GABA-A receptor.Agonist-specific conformational changes in the α1-γ2 subunit interface of the GABA A receptor.Colchicine: a novel positive allosteric modulator of the human 5-hydroxytryptamine3A receptorLigand-specific conformational changes in the alpha1 glycine receptor ligand-binding domainStructural rearrangements in loop F of the GABA receptor signal ligand binding, not channel activation.The benzodiazepine diazepam potentiates responses of α1β2γ2L γ-aminobutyric acid type A receptors activated by either γ-aminobutyric acid or allosteric agonists.Glycine Receptors Caught between Genome and Proteome - Functional Implications of RNA Editing and Splicing.The role of Loop F in the activation of the GABA receptor.The structural basis of function in Cys-loop receptors.Docking of 1,4-benzodiazepines in the alpha1/gamma2 GABA(A) receptor modulator site.The GlyR Extracellular β8-β9 Loop - A Functional Determinant of Agonist Potency.Deciphering the binding mode of Zolpidem to GABA(A) α₁ receptor - insights from molecular dynamics simulation.Impaired Glycine Receptor Trafficking in Neurological Diseases
P2860
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P2860
The F-loop of the GABA A receptor gamma2 subunit contributes to benzodiazepine modulation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The F-loop of the GABA A recep ...... to benzodiazepine modulation.
@en
type
label
The F-loop of the GABA A recep ...... to benzodiazepine modulation.
@en
prefLabel
The F-loop of the GABA A recep ...... to benzodiazepine modulation.
@en
P2860
P356
P1476
The F-loop of the GABA A recep ...... to benzodiazepine modulation.
@en
P2093
Claire L Padgett
Sarah C R Lummis
P2860
P304
P356
10.1074/JBC.M705699200
P407
P577
2007-10-31T00:00:00Z