Allosteric modulators induce distinct movements at the GABA-binding site interface of the GABA-A receptor.

Allosteric modulators induce distinct movements at the GABA-binding site interface of the GABA-A receptor.

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http://www.wikidata.org/entity/Q34519334
Benzodiazepines for generalised anxiety disorder (GAD)Caenorhabditis elegans neuromuscular junction: GABA receptors and ivermectin actionPropofol binding to the resting state of the gloeobacter violaceus ligand-gated ion channel (GLIC) induces structural changes in the inter- and intrasubunit transmembrane domain (TMD) cavitiesHow theories evolved concerning the mechanism of action of barbiturates.SB-205384 is a positive allosteric modulator of recombinant GABAA receptors containing rat α3, α5, or α6 subunit subtypes coexpressed with β3 and γ2 subunits.Engineering a light-regulated GABAA receptor for optical control of neural inhibition.Different residues in the GABAA receptor benzodiazepine binding pocket mediate benzodiazepine efficacy and binding.Structural link between γ-aminobutyric acid type A (GABAA) receptor agonist binding site and inner β-sheet governs channel activation and allosteric drug modulationRegulation of the surface expression of α4β2δ GABAA receptors by high efficacy statesSubunit stoichiometry and arrangement in a heteromeric glutamate-gated chloride channel.Impaired surface αβγ GABA(A) receptor expression in familial epilepsy due to a GABRG2 frameshift mutationNeurosteroid interactions with synaptic and extrasynaptic GABA(A) receptors: regulation of subunit plasticity, phasic and tonic inhibition, and neuronal network excitability.A chimeric prokaryotic-eukaryotic pentameric ligand gated ion channel reveals interactions between the extracellular and transmembrane domains shape neurosteroid modulation.An atypical residue in the pore of Varroa destructor GABA-activated RDL receptors affects picrotoxin block and thymol modulationGABAergic pharmacological activity of propofol related compounds as possible enhancers of general anesthetics and interaction with membranes.A Random Forest Model for Predicting Allosteric and Functional Sites on Proteins.Binding site opening by loop C shift and chloride ion-pore interaction in the GABAA receptor model.
P2860

Allosteric modulators induce distinct movements at the GABA-binding site interface of the GABA-A receptor.

Item
http://www.wikidata.org/entity/Q34519334
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Allosteric modulators induce d ...... erface of the GABA-A receptor.
@ast
Allosteric modulators induce d ...... erface of the GABA-A receptor.
@en
Allosteric modulators induce d ...... erface of the GABA-A receptor.
@nl
type
label
Allosteric modulators induce d ...... erface of the GABA-A receptor.
@ast
Allosteric modulators induce d ...... erface of the GABA-A receptor.
@en
Allosteric modulators induce d ...... erface of the GABA-A receptor.
@nl
prefLabel
Allosteric modulators induce d ...... erface of the GABA-A receptor.
@ast
Allosteric modulators induce d ...... erface of the GABA-A receptor.
@en
Allosteric modulators induce d ...... erface of the GABA-A receptor.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Allosteric modulators induce d ...... erface of the GABA-A receptor.
@en
P2093
P2860
P304
P31
P356
10.1016/J.NEUROPHARM.2010.11.009
P433
P478
P577
P5875
P698
P932