Mechanisms underlying the anticancer activities of the angucycline landomycin E.
about
Fibroblast growth factor receptor-mediated signals contribute to the malignant phenotype of non-small cell lung cancer cells: therapeutic implications and synergism with epidermal growth factor receptor inhibition.Properties of lanK-based regulatory circuit involved in landomycin biosynthesis in Streptomyces cyanogenus S136.11-Deoxylandomycinone and landomycins X-Z, new cytotoxic angucyclin(on)es from a Streptomyces cyanogenus K62 mutant strain.Landomycins P-W, cytotoxic angucyclines from Streptomyces cyanogenus S-136Impact of terminal dimethylation on the resistance profile of α-N-heterocyclic thiosemicarbazonesTailoring enzymes involved in the biosynthesis of angucyclines contain latent context-dependent catalytic activities.Saquayamycins G-K, cytotoxic angucyclines from Streptomyces sp. Including two analogues bearing the aminosugar rednose.Dereplication strategies for targeted isolation of new antitrypanosomal actinosporins A and B from a marine sponge associated-Actinokineospora sp. EG49.Angucyclines: Biosynthesis, mode-of-action, new natural products, and synthesis.Delineation of gilvocarcin, jadomycin, and landomycin pathways through combinatorial biosynthetic enzymology.Synthesis of marmycin A and investigation into its cellular activity.Aminopyrimidoisoquinolinequinone (APIQ) redox cycling is potentiated by ascorbate and induces oxidative stress leading to necrotic-like cancer cell death.Rapid generation of hydrogen peroxide contributes to the complex cell death induction by the angucycline antibiotic landomycin E.Intracellular protein binding patterns of the anticancer ruthenium drugs KP1019 and KP1339.N-methylphenylalanyl-dehydrobutyrine diketopiperazine, an A-factor mimic that restores antibiotic biosynthesis and morphogenesis in Streptomyces globisporus 1912-B2 and Streptomyces griseus 1439.Elucidation of post-PKS tailoring steps involved in landomycin biosynthesis.A method to type the potential angucycline producers in actinomycetes isolated from marine sponges.
P2860
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P2860
Mechanisms underlying the anticancer activities of the angucycline landomycin E.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Mechanisms underlying the anticancer activities of the angucycline landomycin E.
@en
type
label
Mechanisms underlying the anticancer activities of the angucycline landomycin E.
@en
prefLabel
Mechanisms underlying the anticancer activities of the angucycline landomycin E.
@en
P2093
P1476
Mechanisms underlying the anticancer activities of the angucycline landomycin E.
@en
P2093
Alla Korynevska
Bohdan Matselyukh
Leonilla Elbling
Michael Micksche
Rostyslav Stoika
Walter Berger
P304
P356
10.1016/J.BCP.2007.08.026
P407
P577
2007-08-25T00:00:00Z