Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion.
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The regulation of MMP targeting to invadopodia during cancer metastasisCellular traction stresses increase with increasing metastatic potentialRac and Rho GTPases in cancer cell motility controlLack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk.The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasionThe Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis.Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.2D protrusion but not motility predicts growth factor-induced cancer cell migration in 3D collagenThe 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and functionMatrix crosslinking forces tumor progression by enhancing integrin signalingRho, ROCK and actomyosin contractility in metastasis as drug targetsCapturing relevant extracellular matrices for investigating cell migrationIn Vitro Tumor Models: Advantages, Disadvantages, Variables, and Selecting the Right PlatformUtilization of Glycosaminoglycans/Proteoglycans as Carriers for Targeted Therapy DeliveryImplications of the Hybrid Epithelial/Mesenchymal Phenotype in MetastasisPhysical view on migration modesMatrix metalloproteinases in stem cell regulation and cancerConnexins, gap junctions and tissue invasionThe interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasionPhysical biology in cancer. 5. The rocky road of metastasis: the role of cytoskeletal mechanics in cell migratory response to 3D matrix topographyRho GTPases in collective cell migrationA new paradigm for mechanobiological mechanisms in tumor metastasisTumor cell migration in complex microenvironmentsThe development of a novel high throughput computational tool for studying individual and collective cellular migrationProteolytic and non-proteolytic regulation of collective cell invasion: tuning by ECM density and organization.Cells activated for wound repair have the potential to direct collective invasion of an epithelium.Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-βARF6-JIP3/4 regulate endosomal tubules for MT1-MMP exocytosis in cancer invasion.Cells assemble invadopodia-like structures and invade into matrigel in a matrix metalloprotease dependent manner in the circular invasion assayMulti-cellular logistics of collective cell migrationFrom single cells to tissues: interactions between the matrix and human breast cells in real timeMultiparametric classification links tumor microenvironments with tumor cell phenotypeA novel MMP-2 inhibitor 3-azidowithaferin A (3-azidoWA) abrogates cancer cell invasion and angiogenesis by modulating extracellular Par-4TOM1L1 drives membrane delivery of MT1-MMP to promote ERBB2-induced breast cancer cell invasion.Loss of myoferlin redirects breast cancer cell motility towards collective migrationMechanical decision trees for investigating and modulating single-cell cancer invasion dynamicsNuclear migration events throughout developmentTumor cell dormancyExtracellular matrix as target for antitumor therapyInitial steps of metastasis: cell invasion and endothelial transmigration
P2860
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P2860
Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Multi-step pericellular proteo ...... llective cancer cell invasion.
@en
type
label
Multi-step pericellular proteo ...... llective cancer cell invasion.
@en
prefLabel
Multi-step pericellular proteo ...... llective cancer cell invasion.
@en
P2093
P356
P1433
P1476
Multi-step pericellular proteo ...... llective cancer cell invasion.
@en
P2093
Jörg Geiger
Katarina Wolf
M Sharon Stack
Peter Friedl
Yueying Liu
P2888
P304
P356
10.1038/NCB1616
P577
2007-07-08T00:00:00Z
P5875
P6179
1013221253