Galpha12 stimulates apoptosis in epithelial cells through JNK1-mediated Bcl-2 degradation and up-regulation of IkappaBalpha.
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Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame sizePolycystin-1 protein level determines activity of the Galpha12/JNK apoptosis pathway.Gα13 mediates human cytomegalovirus-encoded chemokine receptor US28-induced cell death in melanoma.Gα12 activation in podocytes leads to cumulative changes in glomerular collagen expression, proteinuria and glomerulosclerosis.New benzimidazole acridine derivative induces human colon cancer cell apoptosis in vitro via the ROS-JNK signaling pathway.Stimulation of Dopamine D3 Receptor Attenuates Renal Ischemia-Reperfusion Injury via Increased Linkage With Gα12.G alpha12 is targeted to the mitochondria and affects mitochondrial morphology and motility.G protein α12 (Gα12) is a negative regulator of kidney injury molecule-1-mediated efferocytosis.Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by reversible phosphorylation and dephosphorylation.Role of G12 proteins in oncogenesis and metastasisHeterotrimeric G proteins and apoptosis: intersecting signaling pathways leading to context dependent phenotypesG alpha 12 inhibits alpha2 beta1 integrin-mediated Madin-Darby canine kidney cell attachment and migration on collagen-I and blocks tubulogenesis.Tamoxifen and TRAIL synergistically induce apoptosis in breast cancer cells.Kidney injury molecule-1 protects against Gα12 activation and tissue damage in renal ischemia-reperfusion injury.Identification of polycystin-1 and Gα12 binding regions necessary for regulation of apoptosis.Galpha12 Protects Vascular Endothelial Cells from Serum Withdrawal-Induced Apoptosis through Regulation of miR-155.Cross-talk of alpha tocopherol-associated protein and JNK controls the oxidative stress-induced apoptosis in prostate cancer cells.Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume
P2860
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P2860
Galpha12 stimulates apoptosis in epithelial cells through JNK1-mediated Bcl-2 degradation and up-regulation of IkappaBalpha.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Galpha12 stimulates apoptosis ...... up-regulation of IkappaBalpha.
@en
type
label
Galpha12 stimulates apoptosis ...... up-regulation of IkappaBalpha.
@en
prefLabel
Galpha12 stimulates apoptosis ...... up-regulation of IkappaBalpha.
@en
P2093
P2860
P356
P1476
Galpha12 stimulates apoptosis ...... up-regulation of IkappaBalpha.
@en
P2093
Bradley M Denker
Hideyuki Negoro
Lakshman Gunaratnam
Tianqing Kong
Vijay Yanamadala
P2860
P304
24352-24363
P356
10.1074/JBC.M702804200
P407
P577
2007-06-12T00:00:00Z