Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation. - Test2 - elhamkhani - TriplyDB

Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation.

Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation.

http://www.wikidata.org/entity/Q40204018

about

PKD1 phosphorylation-dependent degradation of SNAIL by SCF-FBXO11 regulates epithelial-mesenchymal transition and metastasis Molecular mechanisms of epithelial-mesenchymal transition Structural basis for the selective nuclear import of the C2H2 zinc-finger protein Snail by importin β Tackling Cancer Stem Cells via Inhibition of EMT Transcription Factors Characterization of the SNAG and SLUG domains of Snail2 in the repression of E-cadherin and EMT induction: modulation by serine 4 phosphorylation Snail acetylation by histone acetyltransferase p300 in lung cancer microRNA-605 promotes cell proliferation, migration and invasion in non-small cell lung cancer by directly targeting LATS2.Multilayer control of the EMT master regulators.Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration, and angiogenesis Epithelial-mesenchymal-transition-like and TGFβ pathways associated with autochthonous inflammatory melanoma development in mice Helicobacter pylori initiates a mesenchymal transition through ZEB1 in gastric epithelial cells.Aberrant large tumor suppressor 2 (LATS2) gene expression correlates with EGFR mutation and survival in lung adenocarcinomas.LATS2 Positively Regulates Polycomb Repressive Complex 2.Regulation of the protein stability of EMT transcription factors Bone morphogenetic protein-7 regulates Snail signaling in carbon tetrachloride-induced fibrosis in the rat liver.Loss of Scribble Promotes Snail Translation through Translocation of HuR and Enhances Cancer Drug Resistance PAR1 participates in the ability of multidrug resistance and tumorigenesis by controlling Hippo-YAP pathway.Snai2 and Snai3 transcriptionally regulate cellular fitness and functionality of T cell lineages through distinct gene programs.Mechanical signals regulate and activate SNAIL1 protein to control the fibrogenic response of cancer-associated fibroblasts Transient SNAIL1 expression is necessary for metastatic competence in breast cancer The Hippo pathway, p53 and cholesterol The collagen receptor discoidin domain receptor 2 stabilizes SNAIL1 to facilitate breast cancer metastasis Nuclear ubiquitination by FBXL5 modulates Snail1 DNA binding and stability.The Role of Snail in EMT and Tumorigenesis.Regulation and functions of mammalian LATS/NDR kinases: looking beyond canonical Hippo signalling.Snail nuclear transport: the gateways regulating epithelial-to-mesenchymal transition?ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types The clinical significance and biological function of large tumour suppressor 2 in hepatocellular carcinoma.TIP60 inhibits metastasis by ablating DNMT1-SNAIL2-driven epithelial-mesenchymal transition program.The LATS1 and LATS2 tumor suppressors: beyond the Hippo pathway.JMJD1C Ensures Mouse Embryonic Stem Cell Self-Renewal and Somatic Cell Reprogramming through Controlling MicroRNA Expression.Hippo and rassf1a Pathways: A Growing Affair Cancer-associated fibroblasts support vascular growth through mechanical force.Regulation of FBXO4-mediated ICAM-1 protein stability in metastatic breast cancer.The regulation of snail: on the ubiquitin edge.Epithelial Mesenchymal Transition in Embryonic Development, Tissue Repair and Cancer: A Comprehensive Overview.SPSB3 targets SNAIL for degradation in GSK-3β phosphorylation-dependent manner and regulates metastasis.Heterozygosity of mitogen-activated protein kinase organizer 1 ameliorates diabetic nephropathy and suppresses epithelial-to-mesenchymal transition-like changes in db/db mice.Interlocked loops trigger lineage specification and stable fates in the Drosophila nervous system.C-terminal domain small phosphatase-like 2 promotes epithelial-to-mesenchymal transition via Snail dephosphorylation and stabilization.

P2860

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P2860

Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation.

http://www.wikidata.org/entity/Q40204018

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

2011年论文

@zh

2011年论文

@zh-cn

name

Lats2 kinase potentiates Snail ...... etention upon phosphorylation.

@en

type

label

Lats2 kinase potentiates Snail ...... etention upon phosphorylation.

@en

prefLabel

Lats2 kinase potentiates Snail ...... etention upon phosphorylation.

@en

P1433

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P2860

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P304

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P1433

The EMBO Journal

P1476

Lats2 kinase potentiates Snail ...... retention upon phosphorylation

@en

P2093

Eva Rodriguez-Aznar

http://www.w3.org/2001/XMLSchema#string

Gregory D Longmore

http://www.w3.org/2001/XMLSchema#string

Hiroshi Nojima

http://www.w3.org/2001/XMLSchema#string

Jose M Mingot

http://www.w3.org/2001/XMLSchema#string

Kun Zhang

http://www.w3.org/2001/XMLSchema#string

Norikazu Yabuta

http://www.w3.org/2001/XMLSchema#string

Robert J Owen

http://www.w3.org/2001/XMLSchema#string

P2860

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

The Ajuba LIM domain protein is a corepressor for SNAG domain mediated repression and participates in nucleocytoplasmic Shuttling

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

Tumor suppressor LATS1 is a negative regulator of oncogene YAP

Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway

Ajuba LIM proteins are snail/slug corepressors required for neural crest development in Xenopus

A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells

A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression

Hit selection with false discovery rate control in genome-scale RNAi screens

P304

29-43

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P31

scholarly article

P356

10.1038/EMBOJ.2011.357

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P407

P433

1

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P478

31

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P50

M. Angela Nieto

P577

2011-09-27T00:00:00Z

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P5875

51666889

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P698

21952048

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

3252572

http://www.w3.org/2001/XMLSchema#string