about
Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatasesLarge-scale structural analysis of the classical human protein tyrosine phosphatomeThe crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1Crystal Structures of ABL-Related Gene (ABL2) in Complex with Imatinib, Tozasertib (VX-680), and a Type I Inhibitor of the Triazole Carbothioamide ClassStructures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound statesPhospholipase C-beta 2 interacts with mitogen-activated protein kinase kinase 3RGS4 inhibits platelet-activating factor receptor phosphorylation and cellular responsesHD-PTP is a catalytically inactive tyrosine phosphatase due to a conserved divergence in its phosphatase domain.Crystal structure of human protein tyrosine phosphatase 14 (PTPN14) at 1.65-A resolution.Non-peptide antagonists, CP-96,345 and RP 67580, distinguish species variants in tachykinin NK1 receptors.Targeting protein tyrosine phosphatase SHP2 for therapeutic intervention.MAPK-specific tyrosine phosphatases: new targets for drug discovery?Differential regulation of formyl peptide and platelet-activating factor receptors. Role of phospholipase Cbeta3 phosphorylation by protein kinase A.Defining the molecular basis of interaction between R3 receptor-type protein tyrosine phosphatases and VE-cadherinAgonist-independent activation of Gz by the 5-hydroxytryptamine1A receptor co-expressed in Spodoptera frugiperda cells. Distinguishing inverse agonists from neutral antagonists.Reconstitution of receptors and GTP-binding regulatory proteins (G proteins) in Sf9 cells. A direct evaluation of selectivity in receptor.G protein coupling.CD148 enhances platelet responsiveness to collagen by maintaining a pool of active Src family kinases.Sequence-specific 1H, 13C and 15N backbone resonance assignments of the 34 kDa catalytic domain of human PTPN7.Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized miceThe biochemical basis of diseaseThe presence of NK3 tachykinin receptors on rat uterusIdentification of a region at the N-terminus of phospholipase C-beta 3 that interacts with G protein beta gamma subunitsHeparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-BTargeting Receptor-Type Protein Tyrosine Phosphatases with Biotherapeutics: Is Outside-in Better than Inside-Out?
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description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
Alastair J. Barr
@ast
Alastair J. Barr
@en
Alastair J. Barr
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Alastair J. Barr
@nl
type
label
Alastair J. Barr
@ast
Alastair J. Barr
@en
Alastair J. Barr
@es
Alastair J. Barr
@nl
prefLabel
Alastair J. Barr
@ast
Alastair J. Barr
@en
Alastair J. Barr
@es
Alastair J. Barr
@nl
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7102666001
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0000-0001-7738-8419