Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis. - Test2 - elhamkhani - TriplyDB

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.

http://www.wikidata.org/entity/Q40336402

about

Current status and perspectives of patient-derived xenograft models in cancer research.Unravelling the biology of SCLC: implications for therapy.Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis.Relevance of genetic alterations in squamous and small cell lung cancer.Small-cell lung cancer: what we know, what we need to know and the path forward.Expression of EZH2 in endometrial carcinoma and its effects on proliferation and invasion of endometrial carcinoma cells.Overcoming resistance to DNA targeted agents by epigenetic activation of Schlafen 11 (SLFN11) expression with class I histone deacetylase inhibitors.Identification of candidate responders for anti-PD-L1/PD-1 immunotherapy, Rova-T therapy, or EZH2 inhibitory therapy in small-cell lung cancer.[Progress of Epigenetic Methylation in Lung Cancer Research].SLFN11 Blocks Stressed Replication Forks Independently of ATR.Small cell lung cancer tumors and preclinical models display heterogeneity of neuroendocrine phenotypes.Epigenetic regulation of cancer progression by EZH2: from biological insights to therapeutic potential.Targeting DNA damage repair in small cell lung cancer and the biomarker landscape.Tumor heterogeneity in small cell lung cancer defined and investigated in pre-clinical mouse models.Sodium Valproate Inhibits Small Cell Lung Cancer Tumor Growth on the Chicken Embryo Chorioallantoic Membrane and Reduces the p53 and EZH2 Expression.Identiﬁcation of candidate biomarkers and pathways associated with SCLC by bioinformatics analysis.Transcriptional deregulation underlying the pathogenesis of small cell lung cancer.Modeling the relationship between baseline lactate dehydrogenase and prognosis in patients with extensive-disease small cell lung cancer: a retrospective cohort study.Modeling small cell lung cancer (SCLC) biology through deterministic and stochastic mathematical models.Frequent epigenetic alterations in polycomb repressive complex 2 in osteosarcoma cell lines.Emerging application of genomics-guided therapeutics in personalized lung cancer treatment.Establishing and Maintaining an Extensive Library of Patient-Derived Xenograft Models.Nucleobase and Nucleoside Analogues: Resistance and Re-Sensitisation at the Level of Pharmacokinetics, Pharmacodynamics and Metabolism Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer

P2860

Q33667686-CB38A3EC-B517-4F82-970B-F5D2723314C3 Q38769421-89EF05AC-8632-47FD-80ED-BA7D7FEECB94 Q41992348-471D9223-DA44-48F9-B024-93B151E88ABD Q44483486-C48067FF-A682-40B7-B019-A60315DF1CD0 Q47595394-0FD18ED8-DDB9-4E5B-A929-CAA435FE72DF Q49236228-A8C3232D-4847-4A99-A336-417A24BC1AC7 Q49390599-E440E9C5-7C08-44AD-9912-440CC35C53EE Q49512731-5C6A6BAF-B60D-4594-891B-75A1DF054EDF Q49958907-16B84C15-27DF-484F-B48B-ADA0958B48EA Q50209876-0B4C3AAC-61EA-47FD-9D3C-45FEB6486255 Q51734136-01637FE8-3E11-43B3-BA68-BE9D3073D46D Q52349529-A1641592-41E8-4E4F-B0DF-41AC97B878FC Q52657032-E09294B6-B91A-4ED0-9A81-4FAB3543C8E4 Q53702193-287B49C7-2D10-4ADC-8431-49947424F0BD Q54118413-2DA1221D-558E-4C7E-94C1-DD25036B552C Q54977757-41ADB373-0514-4829-9358-6CF786279B8E Q55011897-CD220CB8-A8C1-4E55-85D6-A42A8351A48A Q55018803-19F6E3AC-C097-4B75-8473-7AEE9616B77E Q55110585-5B83D4E0-CF42-467E-8793-C567F8399706 Q55261902-9ADB03A2-52C9-419C-BB5B-74FE6D011978 Q55314894-C1371D59-D407-4585-89A4-9832DE426397 Q55380373-3D5105E2-CD71-4640-8CBD-4DD1AC855AAC Q57175017-D2DEFF4C-49F3-4AFE-9799-AB66F4E9BB48 Q58734416-AA793552-5A6C-4636-B00D-EDCD0E39E9A1

P2860

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.

http://www.wikidata.org/entity/Q40336402

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年論文

@yue

2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

@wuu

2017年论文

@zh

2017年论文

@zh-cn

name

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.

@en

type

label

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.

@en

prefLabel

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.

@en

P1433

Q40336402-58622CEA-BF80-4B28-BD04-D744BDDB0608

P1476

Q40336402-017C2B9D-6A58-4928-BE54-0F6B3FA23CE6

P2093

Q40336402-010411F9-9FF8-46D2-A962-AFF830C95814

Q40336402-39E555D2-55DC-4F59-BF99-0F602D12A734

Q40336402-3FCAB55A-4151-4CBB-AE77-5BC6BC77DA17

Q40336402-45488D6C-D594-4850-840A-E0D61833E947

Q40336402-5249CE96-7430-4E21-B5EB-36FF83B5564F

Q40336402-6EF4F434-4A1B-413C-82B9-D00991202B63

Q40336402-85E6DF77-4F0B-4A4F-AFF6-7B99855BAB9F

Q40336402-88768B67-E68B-4270-AACB-EDC89ADB5F51

Q40336402-91292398-8D11-4973-A8AE-F0BF75B142BD

Q40336402-9CF82503-ACE4-4068-B44A-A5F0D0D1460C

P2860

Q40336402-04B08919-F5E1-404B-BD0B-292EB0D21E1B

Q40336402-070DA49F-F751-4A3E-9192-15ADEA19B7F6

Q40336402-0EF89563-A730-4A94-8E36-D013DBDD2B91

Q40336402-10A977A9-CF02-42E6-A2C5-C60CD426EB78

Q40336402-1C12AB06-0AC5-4F04-BF1B-4245634CC2AF

Q40336402-2734ABF9-E082-4405-BB82-2B7325E4E287

Q40336402-31F43355-214C-4301-AF51-6D31AAAA6D2D

Q40336402-32EA845D-4B5C-4898-8E78-DBB9940C0A74

Q40336402-39B36D25-23D8-4931-869D-0FB72E63BF7B

Q40336402-40AEC71D-F588-4AB4-A199-94AEC74337AD

P304

Q40336402-B0998D9D-CD96-4713-AD34-B3E87CEBA8AA

P31

Q40336402-05C55630-D280-460F-B9D9-CBE375571640

P356

Q40336402-5B45ACAC-3170-4E7D-A16E-4F1BA409FB43

P433

Q40336402-EA56D1EA-88C0-4153-8532-3389E495C348

P478

Q40336402-13A5D1D4-BF73-4F0D-8E7C-B2A18312549F

P50

Q40336402-088BB8A9-B925-48BE-905F-E53B5E49F60F

Q40336402-3B70972B-4A77-4C23-8FBB-1B16C7E941EE

Q40336402-3E9008A4-F859-4B5A-867B-F1B2BE2C0165

Q40336402-CF1480B1-005C-4C18-AFCD-AC506E71DFEE

P577

Q40336402-4A5A1204-29DF-4384-A49C-827593F4AB7D

P698

Q40336402-1B171204-3A14-403D-95BB-4D37C2D0D285

P932

Q40336402-CF9DE54A-FBB4-4817-A9F3-CF0CB368738A

P356

J.CCELL.2017.01.006

P1433

P1476

Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis

@en

P2093

Afshin Dowlati

http://www.w3.org/2001/XMLSchema#string

Andy Ni

http://www.w3.org/2001/XMLSchema#string

Elisa de Stanchina

http://www.w3.org/2001/XMLSchema#string

Eric E Gardner

http://www.w3.org/2001/XMLSchema#string

Inna Khodos

http://www.w3.org/2001/XMLSchema#string

John E Campbell

http://www.w3.org/2001/XMLSchema#string

Linde A Miles

http://www.w3.org/2001/XMLSchema#string

Natasha Rekhtman

http://www.w3.org/2001/XMLSchema#string

Paige K Arnold

http://www.w3.org/2001/XMLSchema#string

Patrice Desmeules

http://www.w3.org/2001/XMLSchema#string

P2860

Putative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agents

DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter

A primary xenograft model of small-cell lung cancer reveals irreversible changes in gene expression imposed by culture in vitro

Global cancer statistics, 2012

Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

Factorbook.org: a Wiki-based database for transcription factor-binding data generated by the ENCODE consortium

Signatures of mutational processes in human cancer

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

P304

286-299

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.CCELL.2017.01.006

http://www.w3.org/2001/XMLSchema#string

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

31

http://www.w3.org/2001/XMLSchema#string

P50

P577

2017-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28196596

http://www.w3.org/2001/XMLSchema#string

P932

5313262

http://www.w3.org/2001/XMLSchema#string