about
MKP-1 inhibits high NaCl-induced activation of p38 but does not inhibit the activation of TonEBP/OREBP: opposite roles of p38alpha and p38deltaIncreased insensible water loss contributes to aging related dehydration.Cell cycle-dependent expression of thyroid hormone receptor-beta is a mechanism for variable hormone sensitivity.Mediator of DNA damage checkpoint 1 (MDC1) contributes to high NaCl-induced activation of the osmoprotective transcription factor TonEBP/OREBP.Secretion of von Willebrand factor by endothelial cells links sodium to hypercoagulability and thrombosis.Pax2 expression occurs in renal medullary epithelial cells in vivo and in cell culture, is osmoregulated, and promotes osmotic tolerance.Increased activity of TNAP compensates for reduced adenosine production and promotes ectopic calcification in the genetic disease ACDC.Rapid activation of G2/M checkpoint after hypertonic stress in renal inner medullary epithelial (IME) cells is protective and requires p38 kinase.Ku86 preserves chromatin integrity in cells adapted to high NaCl.Cell cycle delay and apoptosis in response to osmotic stress.Mre11 is expressed in mammalian mitochondria where it binds to mitochondrial DNA.High urea and NaCl carbonylate proteins in renal cells in culture and in vivo, and high urea causes 8-oxoguanine lesions in their DNADNA double-strand breaks induced by high NaCl occur predominantly in gene desertsElevated sodium and dehydration stimulate inflammatory signaling in endothelial cells and promote atherosclerosis.Hypertonic stress response.DNA damage and osmotic regulation in the kidney.Cells adapted to high NaCl have many DNA breaks and impaired DNA repair both in cell culture and in vivo.Cellular response to hyperosmotic stresses.Analysis of DNA breaks, DNA damage response, and apoptosis produced by high NaCl.Cross-Sectional Positive Association of Serum Lipids and Blood Pressure With Serum Sodium Within the Normal Reference Range of 135-145 mmol/L.High NaCl promotes cellular senescence.Ataxia telangiectasia-mutated, a DNA damage-inducible kinase, contributes to high NaCl-induced nuclear localization of transcription factor TonEBP/OREBP.Mitochondrial dysfunction is an early event in high-NaCl-induced apoptosis of mIMCD3 cells.Proliferation and osmotic tolerance of renal inner medullary epithelial cells in vivo and in cell culture.Rate of increase of osmolality determines osmotic tolerance of mouse inner medullary epithelial cells.Toxicity of acetaminophen, salicylic acid, and caffeine for first-passage rat renal inner medullary collecting duct cells.Involvement of endogenous digitalis-like factors in voluntary selection of alcohol by rats.High NaCl causes Mre11 to leave the nucleus, disrupting DNA damage signaling and repair.Effects of expression of p53 and Gadd45 on osmotic tolerance of renal inner medullary cells.Osmotic Stress and DNA DamageThe Saltiness of the Sea Breaks DNA in Marine Invertebrates: Possible Implications for Animal EvolutionProtection of Renal Inner Medullary Epithelial Cells from Apoptosis by Hypertonic Stress-induced p53 ActivationMutations that prevent caspase cleavage of RIPK1 cause autoinflammatory diseaseSuboptimal hydration remodels metabolism, promotes degenerative diseases, and shortens lifeImpaired angiogenesis and extracellular matrix metabolism in Autosomal-Dominant Hyper-IgE Syndrome
P50
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P50
description
hulumtuese
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researcher
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wetenschapper
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հետազոտող
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Natalia I Dmitrieva
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Natalia I Dmitrieva
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Natalia I Dmitrieva
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Natalia I Dmitrieva
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Natalia I Dmitrieva
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type
label
Natalia I Dmitrieva
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Natalia I Dmitrieva
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Natalia I Dmitrieva
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Natalia I Dmitrieva
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Natalia I Dmitrieva
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Natalia I Dmitrieva
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Natalia I Dmitrieva
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Natalia I Dmitrieva
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Natalia I Dmitrieva
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Natalia I Dmitrieva
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P1053
A-2924-2013
P106
P21
P31
P3829
P496
0000-0001-8074-6950