FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts.
about
FRAXE-associated mental retardation protein (FMR2) is an RNA-binding protein with high affinity for G-quartet RNA forming structure5'-UTR RNA G-quadruplexes: translation regulation and targetingFragile x syndromeA direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome.Temporal requirements of the fragile X mental retardation protein in the regulation of synaptic structureWhere Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability DisordersFragile X-like behaviors and abnormal cortical dendritic spines in cytoplasmic FMR1-interacting protein 2-mutant mice.Dicer-derived microRNAs are utilized by the fragile X mental retardation protein for assembly on target RNAsIn vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation proteinA novel function for fragile X mental retardation protein in translational activationThe G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancerDSCR1 interacts with FMRP and is required for spine morphogenesis and local protein synthesisFragile X related protein 1 isoforms differentially modulate the affinity of fragile X mental retardation protein for G-quartet RNA structurePositive feedback regulation of Akt-FMRP pathway protects neurons from cell deathThe autism and schizophrenia associated gene CYFIP1 is critical for the maintenance of dendritic complexity and the stabilization of mature spinesRescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486.CYFIP1 coordinates mRNA translation and cytoskeleton remodeling to ensure proper dendritic spine formationPremutation in the Fragile X Mental Retardation 1 (FMR1) Gene Affects Maternal Zn-milk and Perinatal Brain Bioenergetics and Scaffolding.The role of fragile X mental retardation protein in major mental disorders.Fragile X: a family of disorders.Genetic and systems level analysis of Drosophila sticky/citron kinase and dFmr1 mutants reveals common regulation of genetic networks.New insights into the regulatory function of CYFIP1 in the context of WAVE- and FMRP-containing complexes.The role of the actin cytoskeleton in regulating Drosophila behaviorGlobal signatures of protein and mRNA expression levels.Meeting at the crossroads: common mechanisms in Fragile X and Down syndromePhysiological activation of synaptic Rac>PAK (p-21 activated kinase) signaling is defective in a mouse model of fragile X syndrome.A QUICK screen for Lrrk2 interaction partners--leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics.A presynaptic role for FMRP during protein synthesis-dependent long-term plasticity in Aplysia.BOD1 Is Required for Cognitive Function in Humans and Drosophila.A novel role for the RNA-binding protein FXR1P in myoblasts cell-cycle progression by modulating p21/Cdkn1a/Cip1/Waf1 mRNA stability.Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling.Modulation of dendritic spines and synaptic function by Rac1: a possible link to Fragile X syndrome pathology.Proteomics, ultrastructure, and physiology of hippocampal synapses in a fragile X syndrome mouse model reveal presynaptic phenotypeThe drosophila fragile X protein dFMR1 is required during early embryogenesis for pole cell formation and rapid nuclear division cycles.hnRNP Q regulates Cdc42-mediated neuronal morphogenesis.Differential translation and fragile X syndrome.Rho-linked genes and neurological disorders.Aberrant early-phase ERK inactivation impedes neuronal function in fragile X syndrome.The FMRP/GRK4 mRNA interaction uncovers a new mode of binding of the Fragile X mental retardation protein in cerebellumFragile X mental retardation protein regulates new neuron differentiation in the adult olfactory bulb.
P2860
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P2860
FMRP interferes with the Rac1 pathway and controls actin cytoskeleton dynamics in murine fibroblasts.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
FMRP interferes with the Rac1 ...... ynamics in murine fibroblasts.
@en
type
label
FMRP interferes with the Rac1 ...... ynamics in murine fibroblasts.
@en
prefLabel
FMRP interferes with the Rac1 ...... ynamics in murine fibroblasts.
@en
P2093
P2860
P50
P356
P1476
FMRP interferes with the Rac1 ...... dynamics in murine fibroblasts
@en
P2093
Edward W Khandjian
Elias Bechara
Marie Castets
Sylvie Luche
Thierry Rabilloud
P2860
P304
P356
10.1093/HMG/DDI077
P577
2005-02-09T00:00:00Z