The yeast PRP8 protein interacts directly with pre-mRNA.
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Prp8 protein: at the heart of the spliceosomeThe canonical GU dinucleotide at the 5' splice site is recognized by p220 of the U5 snRNP within the spliceosomeThe human Prp8 protein is a component of both U2- and U12-dependent spliceosomesCharacterization of U6 snRNA-protein interactions.Identification of an RNA-dependent ATPase activity in mammalian U5 snRNPsA novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reactionA U5 small nuclear ribonucleoprotein particle protein involved only in the second step of pre-mRNA splicing in Saccharomyces cerevisiae.The splicing factor PRP2, a putative RNA helicase, interacts directly with pre-mRNAExtragenic suppressors of Saccharomyces cerevisiae prp4 mutations identify a negative regulator of PRP genesDomain analysis of human U5 RNA. Cap trimethylation, protein binding, and spliceosome assemblyThe budding yeast U5 snRNP Prp8 is a highly conserved protein which links RNA splicing with cell cycle progression.Mutational analysis of Saccharomyces cerevisiae U4 small nuclear RNA identifies functionally important domains.Direct interactions between pre-mRNA and six U2 small nuclear ribonucleoproteins during spliceosome assemblyExtensive interactions of PRP8 protein with the 5' and 3' splice sites during splicing suggest a role in stabilization of exon alignment by U5 snRNA.Antisense oligonucleotide binding to U5 snRNP induces a conformational change that exposes the conserved loop of U5 snRNA.Interaction of the yeast splicing factor PRP8 with substrate RNA during both steps of splicing.A dominant negative mutation in the conserved RNA helicase motif 'SAT' causes splicing factor PRP2 to stall in spliceosomes.Roles of PRP8 protein in the assembly of splicing complexes.Motifs IV and V in the DEAH box splicing factor Prp22 are important for RNA unwinding, and helicase-defective Prp22 mutants are suppressed by Prp8.The role of branchpoint-3' splice site spacing and interaction between intron terminal nucleotides in 3' splice site selection in Saccharomyces cerevisiaeTrans mRNA splicing in trypanosomes: cloning and analysis of a PRP8-homologous gene from Trypanosoma brucei provides evidence for a U5-analogous RNP
P2860
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P2860
The yeast PRP8 protein interacts directly with pre-mRNA.
description
1991 nî lūn-bûn
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1991年の論文
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1991年学术文章
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1991年学术文章
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1991年学术文章
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1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
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1991年學術文章
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1991年學術文章
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name
The yeast PRP8 protein interacts directly with pre-mRNA.
@en
type
label
The yeast PRP8 protein interacts directly with pre-mRNA.
@en
prefLabel
The yeast PRP8 protein interacts directly with pre-mRNA.
@en
P2860
P356
P1476
The yeast PRP8 protein interacts directly with pre-mRNA.
@en
P2093
P2860
P304
P356
10.1093/NAR/19.20.5483
P577
1991-10-01T00:00:00Z