PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.
about
Dynamic variations in epithelial-to-mesenchymal transition (EMT), ATM, and SLFN11 govern response to PARP inhibitors and cisplatin in small cell lung cancer.Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition.Small cell lung carcinoma cell line screen of etoposide/carboplatin plus a third agent.Unravelling the biology of SCLC: implications for therapy.Chemosensitive Relapse in Small Cell Lung Cancer Proceeds through an EZH2-SLFN11 Axis.Relevance of genetic alterations in squamous and small cell lung cancer.Inhibition of CHK1 sensitizes Ewing sarcoma cells to the ribonucleotide reductase inhibitor gemcitabine.Target engagement imaging of PARP inhibitors in small-cell lung cancer.Overcoming resistance to DNA targeted agents by epigenetic activation of Schlafen 11 (SLFN11) expression with class I histone deacetylase inhibitors.SLFN11 Blocks Stressed Replication Forks Independently of ATR.Targeting AXL and mTOR Pathway Overcomes Primary and Acquired Resistance to WEE1 Inhibition in Small-Cell Lung Cancer.MCAM Mediates Chemoresistance in Small-Cell Lung Cancer via the PI3K/AKT/SOX2 Signaling Pathway.[Recent Advances and Future Strategies for Small Cell Lung Cancer].Targeting DNA damage repair in small cell lung cancer and the biomarker landscape.[Advances in the Treatment of Relapsed Small Cell Lung Cancer].Autophagy modulates temozolomide-induced cell death in alveolar Rhabdomyosarcoma cellsOptimizing poly (ADP-ribose) polymerase inhibition through combined epigenetic and immunotherapy
P2860
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P2860
PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
PARP Inhibitor Activity Correl ...... ide in Small Cell Lung Cancer.
@en
type
label
PARP Inhibitor Activity Correl ...... ide in Small Cell Lung Cancer.
@en
prefLabel
PARP Inhibitor Activity Correl ...... ide in Small Cell Lung Cancer.
@en
P2093
P2860
P50
P1476
PARP Inhibitor Activity Correl ...... mide in Small Cell Lung Cancer
@en
P2093
Beverly A Teicher
Elisa de Stanchina
Eric E Gardner
Natasha Rekhtman
Patrice Desmeules
Simon N Powell
Valentina E Schneeberger
P2860
P304
P356
10.1158/1078-0432.CCR-16-1040
P407
P577
2016-07-20T00:00:00Z