Phenol sulfotransferase, ST1A3, as the main enzyme catalyzing sulfation of troglitazone in human liver.

Phenol sulfotransferase, ST1A3, as the main enzyme catalyzing sulfation of troglitazone in human liver.

Item
http://www.wikidata.org/entity/Q40717565
In vitro inhibition of human hepatic and cDNA-expressed sulfotransferase activity with 3-hydroxybenzo[a]pyrene by polychlorobiphenylols.Hepatobiliary disposition of troglitazone and metabolites in rat and human sandwich-cultured hepatocytes: use of Monte Carlo simulations to assess the impact of changes in biliary excretion on troglitazone sulfate accumulation.Hepatocellular exposure of troglitazone metabolites in rat sandwich-cultured hepatocytes lacking Bcrp and Mrp2: interplay between formation and excretion.Investigations toward enhanced understanding of hepatic idiosyncratic drug reactions.Drug metabolite profiling and elucidation of drug-induced hepatotoxicity.Inflammatory stress and idiosyncratic hepatotoxicity: hints from animal models.Metabolic bioactivation and drug-related adverse effects: current status and future directions from a pharmaceutical research perspective.Idiosyncratic reactions and metabolism of sulfur-containing drugs.Transcriptional Regulation of Human Cytosolic Sulfotransferase 1C3 by Peroxisome Proliferator-Activated Receptor γ in LS180 Human Colorectal Adenocarcinoma CellsImplications of sulfotransferase activity in interindividual variability in drug response: clinical perspective on current knowledge.Gene expression analysis of troglitazone reveals its impact on multiple pathways in cell culture: a case for in vitro platforms combined with gene expression analysis for early (idiosyncratic) toxicity screening.In vitro/in vivo investigations to examine the gender differences in the pharmacokinetics of novel oral Janus kinase (JAK) inhibitor ASP015K and sulfate metabolite M2 in rats.Sulfation of apomorphine by human sulfotransferases: evidence of a major role for the polymorphic phenol sulfotransferase, SULT1A1.Difference in the Pharmacokinetics and Hepatic Metabolism of Antidiabetic Drugs in Zucker Diabetic Fatty and Sprague-Dawley Rats.Human mass balance, metabolite profile and identification of metabolic enzymes of [¹⁴C]ASP015K, a novel oral janus kinase inhibitor.Metabolism-guided drug design
P2860

Phenol sulfotransferase, ST1A3, as the main enzyme catalyzing sulfation of troglitazone in human liver.

Item
http://www.wikidata.org/entity/Q40717565
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Phenol sulfotransferase, ST1A3 ...... f troglitazone in human liver.
@en
type
label
Phenol sulfotransferase, ST1A3 ...... f troglitazone in human liver.
@en
prefLabel
Phenol sulfotransferase, ST1A3 ...... f troglitazone in human liver.
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P5875
P698
P356
P1433
P1476
Phenol sulfotransferase, ST1A3 ...... f troglitazone in human liver.
@en
P2093
P304
P31
P356
P433
P478
P577
P5875
P698