Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage.
about
Interactions between the Nse3 and Nse4 components of the SMC5-6 complex identify evolutionarily conserved interactions between MAGE and EID FamiliesHuman SMC5/6 complex promotes sister chromatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaksIdentification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complexComposition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complexHuman MMS21/NSE2 is a SUMO ligase required for DNA repairFunctions of Ubiquitin and SUMO in DNA Replication and Replication StressCooperativity of the SUMO and Ubiquitin Pathways in Genome StabilityThe SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans MeiosisSmc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisionsMolecular mimicry of SUMO promotes DNA repairStructural and Functional Insights into the Roles of the Mms21 Subunit of the Smc5/6 ComplexDNA Repair and Global Sumoylation Are Regulated by Distinct Ubc9 Noncovalent ComplexesMechanisms, regulation and consequences of protein SUMOylationRequirement of Nse1, a subunit of the Smc5-Smc6 complex, for Rad52-dependent postreplication repair of UV-damaged DNA in Saccharomyces cerevisiae.Interplay between the Smc5/6 complex and the Mph1 helicase in recombinational repairSumoylation and the structural maintenance of chromosomes (Smc) 5/6 complex slow senescence through recombination intermediate resolution.Cooperation of sumoylated chromosomal proteins in rDNA maintenanceCharacterisation of the SUMO-like domains of Schizosaccharomyces pombe Rad60The SUMO isopeptidase Ulp2p is required to prevent recombination-induced chromosome segregation lethality following DNA replication stressH2A.Z-dependent regulation of cohesin dynamics on chromosome armsSUMO E3 ligase HIGH PLOIDY2 regulates endocycle onset and meristem maintenance in Arabidopsis.Arabidopsis SUMO E3 ligase AtMMS21 regulates root meristem development.SUMO chain formation is required for response to replication arrest in S. pombeIn Favor of Establishment: Regulation of Chromatid Cohesion in PlantsNon-SMC elements 1 and 3 are required for early embryo and seedling development in Arabidopsis.Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligaseThe sumoylation pathway is dysregulated in multiple myeloma and is associated with adverse patient outcome.SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1-mediated DNA damage and genome instability.Sumoylation: a new wrestler in the DNA repair ringRole of SUMO:SIM-mediated protein-protein interaction in non-homologous end joining.The Smc5/6 complex and Esc2 influence multiple replication-associated recombination processes in Saccharomyces cerevisiaeThe Smc5-Smc6 complex is required to remove chromosome junctions in meiosis.Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance.Brc1-dependent recovery from replication stress.NMR metabolomic profiling reveals new roles of SUMOylation in DNA damage responseSUMOylation regulates telomere length by targeting the shelterin subunit Tpz1(Tpp1) to modulate shelterin-Stn1 interaction in fission yeast.The maintenance of chromosome structure: positioning and functioning of SMC complexes.MMS21/HPY2 and SIZ1, two Arabidopsis SUMO E3 ligases, have distinct functions in development.The Smc5-Smc6 complex regulates recombination at centromeric regions and affects kinetochore protein sumoylation during normal growth.Smc5p promotes faithful chromosome transmission and DNA repair in Saccharomyces cerevisiae.
P2860
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P2860
Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
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2005年学术文章
@zh-cn
2005年学术文章
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2005年学术文章
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2005年学术文章
@zh-sg
2005年學術文章
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name
Nse2, a component of the Smc5- ...... or the response to DNA damage.
@en
type
label
Nse2, a component of the Smc5- ...... or the response to DNA damage.
@en
prefLabel
Nse2, a component of the Smc5- ...... or the response to DNA damage.
@en
P2093
P2860
P1476
Nse2, a component of the Smc5- ...... or the response to DNA damage.
@en
P2093
Alan R Lehmann
Elaine Taylor
Emily A Andrews
Felicity Z Watts
John Sergeant
P2860
P304
P356
10.1128/MCB.25.1.185-196.2005
P407
P50
P577
2005-01-01T00:00:00Z