The atrial natriuretic peptide receptor (NPR-A/GC-A) is dephosphorylated by distinct microcystin-sensitive and magnesium-dependent protein phosphatases.
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A familial mutation renders atrial natriuretic Peptide resistant to proteolytic degradationATP-independent activation of natriuretic peptide receptorsMass spectrometric detection and characterization of atypical membrane-bound zinc-sensitive phosphatases modulating GABAA receptorsAlternative splicing of the guanylyl cyclase-A receptor modulates atrial natriuretic peptide signalingGuanylyl cyclase (GC)-A and GC-B activities in ventricles and cardiomyocytes from failed and non-failed human hearts: GC-A is inactive in the failed cardiomyocyte.Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C.Calcineurin regulates homologous desensitization of natriuretic peptide receptor-A and inhibits ANP-induced testosterone production in MA-10 cells.The indolocarbazole, Gö6976, inhibits guanylyl cyclase-A and -B.A cardiac pathway of cyclic GMP-independent signaling of guanylyl cyclase A, the receptor for atrial natriuretic peptideA human skeletal overgrowth mutation increases maximal velocity and blocks desensitization of guanylyl cyclase-B.Reduced ability of C-type natriuretic peptide (CNP) to activate natriuretic peptide receptor B (NPR-B) causes dwarfism in lbab -/- mice.Photoreceptor guanylate cyclase variants: cGMP production under control.Endothelial actions of atrial and B-type natriuretic peptidesRegulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases.Antibody tracking demonstrates cell type-specific and ligand-independent internalization of guanylyl cyclase a and natriuretic peptide receptor C.Homologous desensitization of guanylyl cyclase A, the receptor for atrial natriuretic peptide, is associated with a complex phosphorylation pattern.Adenine nucleotides decrease the apparent Km of endogenous natriuretic peptide receptors for GTP.Csk mediates G-protein-coupled lysophosphatidic acid receptor-induced inhibition of membrane-bound guanylyl cyclase activity.Atrial natriuretic peptide-dependent photolabeling of a regulatory ATP-binding site on the natriuretic peptide receptor-A.Mass spectrometric identification of phosphorylation sites in guanylyl cyclase A and B.Vasopressin-dependent inhibition of the C-type natriuretic peptide receptor, NPR-B/GC-B, requires elevated intracellular calcium concentrations.Pharmacological modulation of the natriuretic peptide system
P2860
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P2860
The atrial natriuretic peptide receptor (NPR-A/GC-A) is dephosphorylated by distinct microcystin-sensitive and magnesium-dependent protein phosphatases.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
The atrial natriuretic peptide ...... ependent protein phosphatases.
@en
type
label
The atrial natriuretic peptide ...... ependent protein phosphatases.
@en
prefLabel
The atrial natriuretic peptide ...... ependent protein phosphatases.
@en
P2860
P356
P1476
The atrial natriuretic peptide ...... ependent protein phosphatases.
@en
P2093
Lincoln R Potter
Paula M Bryan
P2860
P304
16041-16047
P356
10.1074/JBC.M110626200
P407
P577
2002-01-30T00:00:00Z