Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner
about
Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2Cepsilon)Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repairLZAP inhibits p38 MAPK (p38) phosphorylation and activity by facilitating p38 association with the wild-type p53 induced phosphatase 1 (WIP1)Adenovirus E1B 55K represses p53 activation in vitro.PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpointsMice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle controlp53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiationFunctional analysis of the human CDC5L complex and identification of its components by mass spectrometryOncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathwayTargeting protein serine/threonine phosphatases for drug developmentWip1 phosphatase: between p53 and MAPK kinases pathwaysReaction-diffusion systems for spatio-temporal intracellular protein networks: A beginner's guide with two examplesInjury-associated reacquiring of intestinal stem cell functionIdentification and characterization of an unusual double serine/threonine protein phosphatase 2C in the malaria parasite Plasmodium falciparumDephosphorylation of human cyclin-dependent kinases by protein phosphatase type 2C alpha and beta 2 isoformsProtein phosphatase 2C inactivates F-actin binding of human platelet moesinCell cycle regulation and p53 activation by protein phosphatase 2C alphaWip-ing out cancerRegulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphataseMosaic PPM1D mutations are associated with predisposition to breast and ovarian cancerA novel protein phosphatase 2C family member (PP2Czeta) is able to associate with ubiquitin conjugating enzyme 9Wip1 suppresses ovarian cancer metastasis through the ATM/AKT/Snail mediated signalingProtein Ser/Thr phosphatases--the ugly ducklings of cell signalling.Fourier analysis and systems identification of the p53 feedback loopDistinct phosphatases antagonize the p53 response in different phases of the cell cycleMolecular cloning of a functional protein phosphatase 2C (FsPP2C2) with unusual features and synergistically up-regulated by ABA and calcium in dormant seeds of Fagus sylvatica.Dynamics of p53 and NF-κB regulation in response to DNA damage and identification of target proteins suitable for therapeutic intervention.Alternative promoters direct tissue-specific expression of the mouse protein phosphatase 2Cbeta gene.Chromatin immunoprecipitation-based screen to identify functional genomic binding sites for sequence-specific transactivators.A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D.Retinoblastoma loss modulates DNA damage response favoring tumor progressionThe oncogenic phosphatase WIP1 negatively regulates nucleotide excision repairNuclear factor-kappaB (NF-kappaB) is a novel positive transcriptional regulator of the oncogenic Wip1 phosphatase.Phosphatases reverse p53-mediated cell cycle checkpointsTranscriptional response of lymphoblastoid cells to ionizing radiationInhibition of the p38 kinase suppresses the proliferation of human ER-negative breast cancer cellsWIP1 phosphatase as pharmacological target in cancer therapy.Expression of a homeostatic regulator, Wip1 (wild-type p53-induced phosphatase), is temporally induced by c-Jun and p53 in response to UV irradiation.Wild-type p53-induced Phosphatase 1 Deficiency Exacerbates Myocardial Infarction-induced Ischemic Injury.Expression of wild-type p53-induced phosphatase 1 in diabetic epiretinal membranes.
P2860
Q24293513-2ED1B504-FCCF-4C92-851A-D66C06232A70Q24297983-8FCBAAE3-35D8-41E2-B263-33A4F53BC220Q24338854-0413C23C-79A6-45EB-AED6-093B10826BF0Q24523301-00EBB6A4-7F4E-4861-A57F-A216FCD8EF39Q24527393-BB680599-76F0-4090-B162-E4FB1C04D1E2Q24537538-03427121-9E19-4B5E-BAB0-AEBC0E9D1B3FQ24596239-1C57DBBB-D6E6-40F5-ACCF-89791430F752Q24596551-175C6BD8-114D-486D-A2D0-484CF869E9DBQ24607221-6A7F2409-76A0-4E21-BB03-77C68C1604BAQ24658001-F63D2307-8B42-4E2F-9A70-7A7FC902F95BQ26863035-3BD02580-2E11-4B09-871A-1AA5DF719F9AQ26991516-EBF0F01E-E2F5-434E-8BC6-9A0AD29DC06BQ27014475-E9FECD29-49D0-4C99-BC81-95B589EF45CFQ27974424-854DFE37-AF18-49C1-BA53-E4C82F142EABQ28143089-15873F1E-A5C4-437F-A314-1EB9C262A4BCQ28144127-82769F97-284B-4E50-BCA4-9F00B3214778Q28201863-DB39830F-6CAD-44D7-B29E-0F39B660F9D4Q28253700-0D188048-09D6-4D37-BE7B-C0297F2CDE04Q28283888-A0E3D62C-A496-4C36-B7FA-B26BD5AFED1BQ28388006-34FAFD9D-3569-407B-BD46-D7491A3F077CQ28589874-198166B6-A98A-4585-B058-8B7676839127Q28828189-FF8B2E0F-D2B6-412F-8113-BE6906F5BEDFQ30455386-A506D8F7-B841-4968-BB3C-64097C4EB347Q30496058-7BAA48BA-DDB8-4984-AF67-801C596D9662Q30578888-76710253-972D-4BAC-9F2D-488412C2BA60Q31075929-36DDEFDE-91DE-4C19-B106-963C69489FF3Q31090728-3A5A0BFC-6650-45D5-8ED1-ADD079962F2EQ33178826-12AACA39-04BD-42BA-9EFD-C2D95F940EF1Q33226324-CDB08FD9-81B4-4C16-94E8-360186747772Q33294239-88BBD6A5-27A2-415F-8382-D35BFECABC21Q33382723-1B6F5E79-431A-4A2F-AAD9-A5A16222F7CEQ33572384-B4594B9D-77A6-4565-8082-8173E815A0A7Q33648301-791F790A-5260-4A35-8E79-D0C8B52FF047Q33665426-4E1E63FC-097E-4286-B04E-5923101425C4Q33679034-ED89D874-F91D-455A-9370-BB1DC64E5D12Q33698448-E90BB3A3-C08E-474C-BA0F-5476544CE0EDQ33720757-202996BA-0DAB-4A25-B942-5CC8F1B96131Q33726581-F8F30536-9EA4-4228-B147-14530980F620Q33755606-2FD4CC6C-2752-433A-B25C-A9A748413323Q33829214-B25C4CE0-3F75-4AF5-A856-146B61824308
P2860
Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Wip1, a novel human protein ph ...... tion in a p53-dependent manner
@ast
Wip1, a novel human protein ph ...... tion in a p53-dependent manner
@en
Wip1, a novel human protein ph ...... tion in a p53-dependent manner
@en-gb
Wip1, a novel human protein ph ...... tion in a p53-dependent manner
@nl
type
label
Wip1, a novel human protein ph ...... tion in a p53-dependent manner
@ast
Wip1, a novel human protein ph ...... tion in a p53-dependent manner
@en
Wip1, a novel human protein ph ...... tion in a p53-dependent manner
@en-gb
Wip1, a novel human protein ph ...... tion in a p53-dependent manner
@nl
prefLabel
Wip1, a novel human protein ph ...... tion in a p53-dependent manner
@ast
Wip1, a novel human protein ph ...... tion in a p53-dependent manner
@en
Wip1, a novel human protein ph ...... tion in a p53-dependent manner
@en-gb
Wip1, a novel human protein ph ...... tion in a p53-dependent manner
@nl
P2093
P2860
P3181
P356
P1476
Wip1, a novel human protein ph ...... tion in a p53-dependent manner
@en
P2093
G F Vande Woude
K Sakaguchi
M Fiscella
P M O'Connor
W E Mercer
P2860
P304
P3181
P356
10.1073/PNAS.94.12.6048
P407
P577
1997-06-10T00:00:00Z