Characterization of placental bikunin, a novel human serine protease inhibitor.
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Pro-urokinase-type plasminogen activator is a substrate for hepsinThe protease inhibitor bikunin, a novel anti-metastatic agentRegulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in miceHepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (HAI-1B) and HAI-2.Hepatocyte growth factor activator inhibitor type 1 is a specific cell surface binding protein of hepatocyte growth factor activator (HGFA) and regulates HGFA activity in the pericellular microenvironmentTissue expression, protease specificity, and Kunitz domain functions of hepatocyte growth factor activator inhibitor-1B (HAI-1B), a new splice variant of HAI-1Expression of hepatocyte growth factor activator inhibitor type 2 (HAI-2) in human testis: identification of a distinct transcription start site for the HAI-2 gene in testisQuantitative mass spectrometry analysis using PAcIFIC for the identification of plasma diagnostic biomarkers for abdominal aortic aneurysmReduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activationInhibition of influenza virus infection and hemagglutinin cleavage by the protease inhibitor HAI-2.Sequence and conformational specificity in substrate recognition: several human Kunitz protease inhibitor domains are specific substrates of mesotrypsin.The crystal structure of a multidomain protease inhibitor (HAI-1) reveals the mechanism of its auto-inhibition.Unusual accelerated rate of deletions and insertions in toxin genes in the venom glands of the pygmy copperhead (Austrelaps labialis) from Kangaroo islandExpression, purification and characterization of the second Kunitz-type protease inhibitor domain of the human WFIKKN protein.Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs).Engineering kunitz domain 1 (KD1) of human tissue factor pathway inhibitor-2 to selectively inhibit fibrinolysis: properties of KD1-L17R variantEmerging multifunctional aspects of cellular serine proteinase inhibitors in tumor progression and tissue regeneration.Roles of hepatocyte growth factor activator (HGFA) and its inhibitor HAI-1 in the regeneration of injured gastrointestinal mucosa.The proteoglycan bikunin has a defined sequence.Bikunin present in human peritoneal fluid is in part derived from the interaction of serum with peritoneal mesothelial cellsMetastatic progression and gene expression between breast cancer cell lines from African American and Caucasian womenPathophysiology and diagnostic value of urinary trypsin inhibitors.Atypical reactive center Kunitz-type inhibitor from the sea anemone Heteractis crispa.SPINT2 Deregulation in Prostate CarcinomaPotent inhibition and global co-localization implicate the transmembrane Kunitz-type serine protease inhibitor hepatocyte growth factor activator inhibitor-2 in the regulation of epithelial matriptase activity.Loss of matriptase suppression underlies spint1 mutation-associated ichthyosis and postnatal lethality.Natural and engineered plasmin inhibitors: applications and design strategies.Recent advances on plasmin inhibitors for the treatment of fibrinolysis-related disorders.Regulation of pericellular proteolysis by hepatocyte growth factor activator inhibitor type 1 (HAI-1) in trophoblast cells.Inhibitors of kallikrein-related peptidases: An overview.A simple procedure for isolating microgram quantities of biologically active bikunin from human urine.Neutrophil elastase activates near-silent epithelial Na+ channels and increases airway epithelial Na+ transport.Upregulation of HGF activator inhibitor type 1 but not type 2 along with regeneration of intestinal mucosa.Use of representational difference analysis to study the effect of TGFB on the expression profile of a pancreatic cancer cell line.Structural analysis of bikunin glycosaminoglycan.Activation of hepatocyte growth factor (HGF) by endogenous HGF activator is required for metanephric kidney morphogenesis in vitro.Na+ transport in normal and CF human bronchial epithelial cells is inhibited by BAY 39-9437.A Kazal-like extracellular serine protease inhibitor from Phytophthora infestans targets the tomato pathogenesis-related protease P69B.The Kunitz Domain I of Hepatocyte Growth Factor Activator Inhibitor-2 Inhibits Matriptase Activity and Invasive Ability of Human Prostate Cancer Cells.A broad spectrum Kunitz type serine protease inhibitor secreted by the hookworm Ancylostoma ceylanicum.
P2860
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P2860
Characterization of placental bikunin, a novel human serine protease inhibitor.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Characterization of placental bikunin, a novel human serine protease inhibitor.
@en
type
label
Characterization of placental bikunin, a novel human serine protease inhibitor.
@en
prefLabel
Characterization of placental bikunin, a novel human serine protease inhibitor.
@en
P2093
P2860
P356
P1476
Characterization of placental bikunin, a novel human serine protease inhibitor.
@en
P2093
Delaria KA
Roczniak SO
Tamburini PP
P2860
P304
12209-12214
P356
10.1074/JBC.272.18.12209
P407
P577
1997-05-01T00:00:00Z