about
Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8The G-patch protein Spp2 couples the spliceosome-stimulated ATPase activity of the DEAH-box protein Prp2 to catalytic activation of the spliceosomeA composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing.Novel regulatory principles of the spliceosomal Brr2 RNA helicase and links to retinal disease in humans.The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation.The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA.Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors.
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Q27684693-1483369D-6385-409C-9522-DBA47056D8E6Q27938864-5CE6FE6C-3382-4080-8C14-43BD95ED8C13Q33285649-45E4AD43-4975-4C7C-AD80-75E4FACCCD5CQ38197052-6F960620-09F3-4834-9EA6-BE9531D5876DQ41310559-A1DDE9D9-28CF-4A6E-828F-7777C77D310AQ41468360-285CCB4A-C343-42A4-8684-0DFAEC2A9627Q52352931-22770D62-76EA-4122-A0C8-4EC270BD77E7
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description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Sina Mozaffari-Jovin
@ast
Sina Mozaffari-Jovin
@en
Sina Mozaffari-Jovin
@es
Sina Mozaffari-Jovin
@sl
type
label
Sina Mozaffari-Jovin
@ast
Sina Mozaffari-Jovin
@en
Sina Mozaffari-Jovin
@es
Sina Mozaffari-Jovin
@sl
prefLabel
Sina Mozaffari-Jovin
@ast
Sina Mozaffari-Jovin
@en
Sina Mozaffari-Jovin
@es
Sina Mozaffari-Jovin
@sl
P106
P21
P31
P496
0000-0003-4410-0460