The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.
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Sirtuin functions and modulation: from chemistry to the clinicPhysiological and pathological implications of 5-hydroxymethylcytosine in diseasesEpigenetic regulatory functions of DNA modifications: 5-methylcytosine and beyondDeciphering the Epigenetic Code in Embryonic and Dental Pulp Stem CellsQSEA-modelling of genome-wide DNA methylation from sequencing enrichment experiments.Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem CellsPI3K/AKT/mTOR Signaling Mediates Valproic Acid-Induced Neuronal Differentiation of Neural Stem Cells through Epigenetic Modifications.A Chemical Biology Approach to Reveal Sirt6-targeted Histone H3 Sites in Nucleosomes.MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.The Commercial Antibodies Widely Used to Measure H3 K56 Acetylation Are Non-Specific in Human and Drosophila Cells.Genome-wide alteration of 5-hydroxymenthylcytosine in a mouse model of Alzheimer's disease.Sirtuin-6 deficiency exacerbates diabetes-induced impairment of wound healing.Sirtuin-dependent clock control: new advances in metabolism, aging and cancerThe Sirt6 gene: Does it play a role in tooth development?SIRT6 polymorphism rs117385980 is associated with longevity and healthy aging in Finnish men.Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes.DNA methylation dynamics in neurogenesis.SIRT6: Novel Mechanisms and Links to Aging and Disease.SIRT6 promotes osteogenic differentiation of mesenchymal stem cells through BMP signaling.Sirt6 alters adult hippocampal neurogenesis.Sirtuin 6 inhibits epithelial to mesenchymal transition during idiopathic pulmonary fibrosis via inactivating TGF-β1/Smad3 signaling.As"SIRT"ing the role of an epigenetic modifier in hematopoietic stem cell homeostasis.Tet-mediated DNA hydroxymethylation regulates retinal neurogenesis by modulating cell-extrinsic signaling pathways.Age-associated hydroxymethylation in human bone-marrow mesenchymal stem cells.LncPRESS1 Is a p53-Regulated LncRNA that Safeguards Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56.Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways.Cell Fate by SIRT6 and TETs.5-hydroxymethylcytosine marks postmitotic neural cells in the adult and developing vertebrate central nervous system.Sirtuins at the crossroads of stemness, aging, and cancer.Epigenetic control of early neurodegenerative events in diabetic retinopathy by the histone deacetylase SIRT6.Prenatal Exposure to Mercury: Associations with Global DNA Methylation and Hydroxymethylation in Cord Blood and in Childhood.SIRT6-mediated transcriptional suppression of Txnip is critical for pancreatic beta cell function and survival in mice.Expression Levels of Warburg-Effect Related microRNAs Correlate with each Other and that of Histone Deacetylase Enzymes in Adult Hematological Malignancies with Emphasis on Acute Myeloid Leukemia.Global H3.3 dynamic deposition defines its bimodal role in cell fate transition.SIRT6 facilitates directional telomere movement upon oxidative damage.An inactivating mutation in the histone deacetylase SIRT6 causes human perinatal lethality.PCGF5 is required for neural differentiation of embryonic stem cells.Epigenetic Regulations in Neural Stem Cells and Neurological Diseases.
P2860
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P2860
The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The histone deacetylase SIRT6 ...... on of 5-hydroxymethylcytosine.
@en
type
label
The histone deacetylase SIRT6 ...... on of 5-hydroxymethylcytosine.
@en
prefLabel
The histone deacetylase SIRT6 ...... on of 5-hydroxymethylcytosine.
@en
P2093
P2860
P356
P1433
P1476
The histone deacetylase SIRT6 ...... ion of 5-hydroxymethylcytosine
@en
P2093
Adrianne Gladden
Alon Goren
Anjana Rao
Barbara Martinez-Pastor
Cesar A Sommer
Dafne M Silberman
Gustavo Mostoslavsky
Jean-Pierre Etchegaray
Kenneth N Ross
P2860
P2888
P304
P356
10.1038/NCB3147
P577
2015-04-27T00:00:00Z