Expression of cancer related BRCA1 missense variants decreases MMS-induced recombination in Saccharomyces cerevisiae without altering its nuclear localization.

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What can yeast tell us about breast cancer?Functional Interaction Between and DNA Repair in Yeast May Uncover a Role of , and Somatic Variants in Cancer Development

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Expression of cancer related BRCA1 missense variants decreases MMS-induced recombination in Saccharomyces cerevisiae without altering its nuclear localization.

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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Expression of cancer related B ...... ring its nuclear localization.

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Expression of cancer related B ...... ring its nuclear localization.

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Expression of cancer related B ...... ring its nuclear localization.

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Expression of cancer related B ...... ring its nuclear localization.

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Martina Vitello

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Samuele Lodovichi

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Tiziana Cervelli

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P2860

Functional analysis of human MLH1 and MSH2 missense variants and hybrid human-yeast MLH1 proteins in Saccharomyces cerevisiae

The BRCT domain is a phospho-protein binding domain

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks.

Hereditary nonpolyposis colorectal cancer in 95 families: differences and similarities between mutation-positive and mutation-negative kindreds

Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains

STRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1

Homologous recombination in DNA repair and DNA damage tolerance

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution

P304

2723-2731

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scholarly article

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10.1080/15384101.2016.1215389

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Alvaro Galli

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2016-08-02T00:00:00Z

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27484786

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5053555

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Expression of cancer related BRCA1 missense variants decreases MMS-induced recombination in Saccharomyces cerevisiae without altering its nuclear localization.

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P2860

P2860

Expression of cancer related BRCA1 missense variants decreases MMS-induced recombination in Saccharomyces cerevisiae without altering its nuclear localization.

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