BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures - Test2 - elhamkhani - TriplyDB

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

http://www.wikidata.org/entity/Q24606873

about

The Werner syndrome protein is distinguished from the Bloom syndrome protein by its capacity to tightly bind diverse DNA structures The BRCA1/2 pathway prevents hematologic cancers in addition to breast and ovarian cancers Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome Regulation and localization of the Bloom syndrome protein in response to DNA damage Chk2 activation dependence on Nbs1 after DNA damage BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations.SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure MutS homologue hMSH4: interaction with eIF3f and a role in NHEJ-mediated DSB repair BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity Fas-associated death domain protein interacts with methyl-CpG binding domain protein 4: a potential link between genome surveillance and apoptosis RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II.IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection The interaction of PP1 with BRCA1 and analysis of their expression in breast tumors TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells Werner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distribution Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome Recql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers.ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation Hereditary nonpolyposis colorectal cancer in 95 families: differences and similarities between mutation-positive and mutation-negative kindreds Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation.Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage A Mammalian bromodomain protein, brd4, interacts with replication factor C and inhibits progression to S phase hSnm1 colocalizes and physically associates with 53BP1 before and after DNA damage Distinct functional domains of nibrin mediate Mre11 binding, focus formation, and nuclear localization Profiling and verification of gene expression patterns in normal and malignant human prostate tissues by cDNA microarray analysis Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin Regulation of RelA (p65) function by the large subunit of replication factor C MPS1-dependent mitotic BLM phosphorylation is important for chromosome stability Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1 Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response The RecQ DNA helicases in DNA repair Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1 ATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases

P2860

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P2860

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

http://www.wikidata.org/entity/Q24606873

description

2000 nî lūn-bûn

@nan

2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2000年の論文

@ja

2000年論文

@yue

2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

@zh-mo

2000年論文

@zh-tw

2000年论文

@wuu

name

BASC, a super complex of BRCA1 ...... air of aberrant DNA structures

@ast

BASC, a super complex of BRCA1 ...... air of aberrant DNA structures

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BASC, a super complex of BRCA1 ...... air of aberrant DNA structures

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type

label

BASC, a super complex of BRCA1 ...... air of aberrant DNA structures

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BASC, a super complex of BRCA1 ...... air of aberrant DNA structures

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BASC, a super complex of BRCA1 ...... air of aberrant DNA structures

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prefLabel

BASC, a super complex of BRCA1 ...... air of aberrant DNA structures

@ast

BASC, a super complex of BRCA1 ...... air of aberrant DNA structures

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BASC, a super complex of BRCA1 ...... air of aberrant DNA structures

@nl

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Q24606873-4523598A-CCA6-4B4B-8F4A-AD072FCBF3D1

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P1433

Genes & Development

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BASC, a super complex of BRCA1 ...... air of aberrant DNA structures

@en

P2093

D Cortez

http://www.w3.org/2001/XMLSchema#string

J Qin

http://www.w3.org/2001/XMLSchema#string

N Neff

http://www.w3.org/2001/XMLSchema#string

P Yazdi

http://www.w3.org/2001/XMLSchema#string

S J Elledge

http://www.w3.org/2001/XMLSchema#string

Y Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

The Bloom's syndrome gene product is homologous to RecQ helicases

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

Histone-like TAFs within the PCAF histone acetylase complex

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

Replication factor C recognizes 5'-phosphate ends of telomeres

P304

927-39

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scholarly article

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667277

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8

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14

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2000-04-15T00:00:00Z

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10783165

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P921

protein structure

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316544

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