Inhibition of the Ser-Thr phosphatases PP1 and PP2A by naturally occurring toxins.
about
CRHSP-24 phosphorylation is regulated by multiple signaling pathways in pancreatic acinar cellsGBPI, a novel gastrointestinal- and brain-specific PP1-inhibitory protein, is activated by PKC and inactivated by PKAIs protein phosphatase inhibition responsible for the toxic effects of okadaic Acid in animals?Post-translational regulation of the Drosophila circadian clock requires protein phosphatase 1 (PP1)Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1Phosphorylation of the nuclear transport machinery down-regulates nuclear protein import in vitroRequirement of Cyclin/Cdk2 and protein phosphatase 1 activity for chromatin assembly factor 1-dependent chromatin assembly during DNA synthesisProtein phosphatase 2A interacts with the Src kinase substrate p130(CAS)Phosphorylation-dependent functional coupling of hSlo calcium-dependent potassium channel and its hbeta 4 subunitTotal synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: impact on PP2A inhibitionCaerulein-induced intracellular pancreatic zymogen activation is dependent on calcineurin.Interleukin-23 production in dendritic cells is negatively regulated by protein phosphatase 2AIdentification of differentially expressed genes in SHSY5Y cells exposed to okadaic acid by suppression subtractive hybridization.Norcantharidin analogues: a patent review (2006 - 2010).The role of serine/threonine protein phosphatases in exocytosisPeptides with anticancer use or potential.GENE EXPRESSION PROFILING OF HUMAN LIVER CARCINOMA (HepG2) CELLS EXPOSED TO THE MARINE TOXIN OKADAIC ACID.Discovery of protein phosphatase 2C inhibitors by virtual screening.Regulation of vascular endothelial cell barrier function and cytoskeleton structure by protein phosphatases of the PPP family.A structural mechanism for maintaining the 'on-state' of the CaMKII memory switch in the post-synaptic density.PP1 control of M phase entry exerted through 14-3-3-regulated Cdc25 dephosphorylation.Complex phosphatase regulation of Ca2+-activated Cl- currents in pulmonary arterial smooth muscle cells.Calyculins and related marine natural products as serine-threonine protein phosphatase PP1 and PP2A inhibitors and total syntheses of calyculin A, B, and C.Cholinesterase inhibitors: a patent review (2007 - 2011).Cantharidin-based small molecules as potential therapeutic agents.Synthetic Strategies Employed for the Construction of Fostriecin and Related Natural Products.Long-term depression-associated signaling is required for an in vitro model of NMDA receptor-dependent synapse pruning.Epigallocatechin-3-gallate and penta-O-galloyl-β-D-glucose inhibit protein phosphatase-1.Identification of a hydrogen peroxide-induced PP1-JNK1-Sp1 signaling pathway for gene regulation.SV40 large T antigen promotes dephosphorylation of p130.Adhesion regulation of stromal cell-derived factor-1 activation of ERK in lymphocytes by phosphatases.The atrial natriuretic peptide receptor (NPR-A/GC-A) is dephosphorylated by distinct microcystin-sensitive and magnesium-dependent protein phosphatases.Phosphorylation is required for alteration of kv1.5 K(+) channel function by the Kvbeta1.3 subunit.Dictyostelium discoideum protein phosphatase-1 catalytic subunit exhibits distinct biochemical properties.Passive mechanical forces upregulate the fast myosin heavy chain IId/x via integrin and p38 MAP kinase activation in a primary muscle cell culture.Structure and conformational analysis of spiroketals from 6-O-methyl-9(E)-hydroxyiminoerythronolide A.A type-1 phosphoprotein phosphatase from a dinoflagellate as a possible component of the circadian mechanism.Crystal structure and mutagenesis of a protein phosphatase-1:calcineurin hybrid elucidate the role of the beta12-beta13 loop in inhibitor binding.The core structures of roseophilin and the prodigiosin alkaloids define a new class of protein tyrosine phosphatase inhibitors.Protein phosphatase 2A regulates apoptosis in neutrophils by dephosphorylating both p38 MAPK and its substrate caspase 3.
P2860
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P2860
Inhibition of the Ser-Thr phosphatases PP1 and PP2A by naturally occurring toxins.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Inhibition of the Ser-Thr phosphatases PP1 and PP2A by naturally occurring toxins.
@en
type
label
Inhibition of the Ser-Thr phosphatases PP1 and PP2A by naturally occurring toxins.
@en
prefLabel
Inhibition of the Ser-Thr phosphatases PP1 and PP2A by naturally occurring toxins.
@en
P2093
P1476
Inhibition of the Ser-Thr phosphatases PP1 and PP2A by naturally occurring toxins.
@en
P2093
Chamberlin AR
Sheppeck JE 2nd
P304
P356
10.1016/S0968-0896(97)00146-6
P407
P577
1997-09-01T00:00:00Z