Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice. - Test2 - elhamkhani - TriplyDB

Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice.

Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice.

http://www.wikidata.org/entity/Q41681261

about

Advances in antibiotic therapy in the critically ill Circulating Pneumolysin Is a Potent Inducer of Cardiac Injury during Pneumococcal Infection Prevalence, pathogenesis, therapy, and prevention of cardiovascular events in patients with community-acquired pneumonia.Engineered nanoparticles mimicking cell membranes for toxin neutralization.Clinical Streptococcus pneumoniae isolates induce differing CXCL8 responses from human nasopharyngeal epithelial cells which are reduced by liposomes.Detoxification of Organophosphate Poisoning Using Nanoparticle Bioscavengers Streptococcus pneumoniae disrupts pulmonary immune defence via elastase release following pneumolysin-dependent neutrophil lysis.How nanotechnology-enabled concepts could contribute to the prevention, diagnosis and therapy of bacterial infections.Nano-antidotes for drug overdose and poisoning.Precision medicine for the treatment of severe pneumonia in intensive care.Multivalent Inhibitors of Channel-Forming Bacterial Toxins.What if there were no new antibiotics? A look at alternatives.Pharmacological Targeting of the Host-Pathogen Interaction: Alternatives to Classical Antibiotics to Combat Drug-Resistant Superbugs.A sphingolipid mechanism for behavioral extinction.A Red Blood Cell Membrane-Camouflaged Nanoparticle Counteracts Streptolysin O-Mediated Virulence Phenotypes of Invasive Group A Streptococcus.Pneumolysin activates neutrophil extracellular trap formation.Non-antibiotic treatments for bacterial diseases in an era of progressive antibiotic resistance.Nanoparticle-based local antimicrobial drug delivery.Robust onionlike structures with magnetic and photodynamic properties formed by a fullerene C60-POM hybrid.Liposomes as novel anti-infectives targeting bacterial virulence factors?Multifaceted Role of Pneumolysin in the Pathogenesis of Myocardial Injury in Community-Acquired Pneumonia.Recent advances in nanomedicine for sepsis treatment.Improving the fate of severely infected patients: the promise of anti-toxin treatments and superiority trials.Nanoparticles in the clinic.Annexins in Translational Research: Hidden Treasures to Be Found.Liposomal Therapy Attenuates Dermonecrosis Induced by Community-Associated Methicillin-Resistant Staphylococcus aureus by Targeting α-Type Phenol-Soluble Modulins and α-Hemolysin

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P2860

Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice.

http://www.wikidata.org/entity/Q41681261

description

2014 nî lūn-bûn

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2014年の論文

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Engineered liposomes sequester ...... e invasive infections in mice.

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Engineered liposomes sequester ...... e invasive infections in mice.

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Engineered liposomes sequester ...... e invasive infections in mice.

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Nature Biotechnology

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Engineered liposomes sequester ...... e invasive infections in mice.

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Annette Draeger

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Aras Kadioglu

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Brian D Henry

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Eduard B Babiychuk

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Heidi Wolfmeier

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Jörg Steinmann

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Kathrin Mühlemann

http://www.w3.org/2001/XMLSchema#string

Laura Bricio-Moreno

http://www.w3.org/2001/XMLSchema#string

Lukasz Japtok

http://www.w3.org/2001/XMLSchema#string

Michael J Edwards

http://www.w3.org/2001/XMLSchema#string

P2860

Cholesterol-dependent cytolysins, a family of versatile pore-forming toxins

RTX proteins: a highly diverse family secreted by a common mechanism

Functional rafts in cell membranes

Poring over pores: alpha-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

Evidence that clustered phosphocholine head groups serve as sites for binding and assembly of an oligomeric protein pore.

Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.

Improved efficacy of ciprofloxacin administered in polyethylene glycol-coated liposomes for treatment of Klebsiella pneumoniae pneumonia in rats.

Bacterial virulence as a target for antimicrobial chemotherapy.

Neurotoxicity of pneumolysin, a major pneumococcal virulence factor, involves calcium influx and depends on activation of p38 mitogen-activated protein kinase.

P2888

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81-88

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10.1038/NBT.3037

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1

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33

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Daniel R. Neill

Burkhard Kleuser

Katrin Anne Becker

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2014-11-02T00:00:00Z

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267738218

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1021034378

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25362245

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