Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
about
The nuts and bolts of the endogenous spliceosomeCryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feastMotif co-regulation and co-operativity are common mechanisms in transcriptional, post-transcriptional and post-translational regulationPrp40 and early events in splice site definitionSpecificity and nonspecificity in RNA-protein interactionsStructure of a yeast spliceosome at 3.6-angstrom resolutionMutations in spliceosomal proteins and retina degenerationMechanisms and Regulation of Alternative Pre-mRNA SplicingSMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.Structure-function analysis and genetic interactions of the Yhc1, SmD3, SmB, and Snp1 subunits of yeast U1 snRNP and genetic interactions of SmD3 with U2 snRNP subunit Lea1.On the path to genetic novelties: insights from programmed DNA elimination and RNA splicing.Two Routes to Genetic Suppression of RNA Trimethylguanosine Cap Deficiency via C-Terminal Truncation of U1 snRNP Subunit Snp1 or Overexpression of RNA Polymerase Subunit Rpo26mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster.Recognizing the 35th anniversary of the proposal that snRNPs are involved in splicing.Proteogenomic analysis reveals alternative splicing and translation as part of the abscisic acid response in Arabidopsis seedlings.Vemurafenib-resistant BRAF selects alternative branch points different from its wild-type BRAF in intron 8 for RNA splicing.Therapeutic activity of modified U1 core spliceosomal particlesA U1 snRNP-specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchangeDetection of RNA-Protein Interactions in Living Cells with SHAPE.Structure-function analysis and genetic interactions of the SmG, SmE, and SmF subunits of the yeast Sm protein ring.Structural basis for the recognition of spliceosomal SmN/B/B' proteins by the RBM5 OCRE domain in splicing regulationBiophysical characterization of the structural change of Nopp140, an intrinsically disordered protein, in the interaction with CK2α.Re-refinement of the spliceosomal U4 snRNP core-domain structure.Dithiothreitol (DTT) Acts as a Specific, UV-inducible Cross-linker in Elucidation of Protein-RNA Interactions.Dynamics and consequences of spliceosome E complex formation.Transcriptome and long noncoding RNA sequencing of three extracellular vesicle subtypes released from the human colon cancer LIM1863 cell line.Methodologies for studying the spliceosome's RNA dynamics with single-molecule FRET.Lights, camera, action! Capturing the spliceosome and pre-mRNA splicing with single-molecule fluorescence microscopy.Noncanonical registers and base pairs in human 5' splice-site selection.Structure and conformational plasticity of the U6 small nuclear ribonucleoprotein core.Splicing Factor Mutations in Myelodysplasias: Insights from Spliceosome Structures.Understanding pre-mRNA splicing through crystallography.A close-up look at the spliceosome, at last.Structural modeling of protein-RNA complexes using crosslinking of segmentally isotope-labeled RNA and MS/MSStructure-function analysis and genetic interactions of the Luc7 subunit of the Saccharomyces cerevisiae U1 snRNP.High-Resolution Mapping of RNA-Binding Regions in the Nuclear Proteome of Embryonic Stem Cells.CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicingAn intimate view of a spliceosome component.A new communication hub in the RNA world.A Challenging Pie to Splice: Drugging the Spliceosome.
P2860
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P248
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P2860
Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Crystal structure of human U1 ...... of 5' splice site recognition.
@en
type
label
Crystal structure of human U1 ...... of 5' splice site recognition.
@en
prefLabel
Crystal structure of human U1 ...... of 5' splice site recognition.
@en
P2093
P2860
P921
P356
P1433
P1476
Crystal structure of human U1 ...... of 5' splice site recognition.
@en
P2093
Anne-Marie M van Roon
Kiyoshi Nagai
Yasushi Kondo
P2860
P356
10.7554/ELIFE.04986
P407
P577
2015-01-02T00:00:00Z