Unmasking determinants of specificity in the human kinome.
about
Large-Scale Off-Target Identification Using Fast and Accurate Dual Regularized One-Class Collaborative Filtering and Its Application to Drug RepurposingProviding data science support for systems pharmacology and its implications to drug discoveryRole of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1.Identification and classification of small molecule kinases: insights into substrate recognition and specificity.Keeping Signals Straight: How Cells Process Information and Make Decisions.Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.Systems Approaches to Cancer BiologyExploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution.PhosphoPredict: A bioinformatics tool for prediction of human kinase-specific phosphorylation substrates and sites by integrating heterogeneous feature selection.Kinase activity ranking using phosphoproteomics data (KARP) quantifies the contribution of protein kinases to the regulation of cell viability.Neomorphic mutations create therapeutic challenges in cancer.Functional variomics and network perturbation: connecting genotype to phenotype in cancer.Distinct distributions of genomic features of the 5' and 3' partners of coding somatic cancer gene fusions: arising mechanisms and functional implicationsSrc defines a new pool of EGFR substrates.Protein interaction perturbation profiling at amino-acid resolution.Phosphoproteomics-Based Profiling of Kinase Activities in Cancer Cells.Tissue-Specific Signaling Networks Rewired by Major Somatic Mutations in Human Cancer Revealed by Proteome-Wide Discovery.Systems medicine approaches for peptide array-based protein kinase profiling: progress and prospects.Homing in: Mechanisms of Substrate Targeting by Protein Kinases.Most yeast SH3 domains bind peptide targets with high intrinsic specificity.In Vivo Phosphoproteome Analysis Reveals Kinome Reprogramming in Hepatocellular Carcinoma.Classifying tumors by supervised network propagation.Hierarchical Organization Endows the Kinase Domain with Regulatory PlasticityProtein Kinases: Physiological Roles in Cell Signalling
P2860
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P2860
Unmasking determinants of specificity in the human kinome.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Unmasking determinants of specificity in the human kinome.
@en
type
label
Unmasking determinants of specificity in the human kinome.
@en
prefLabel
Unmasking determinants of specificity in the human kinome.
@en
P2093
P2860
P1433
P1476
Unmasking determinants of specificity in the human kinome
@en
P2093
Antonio Palmeri
Benjamin E Turk
Chad J Miller
Hua Jane Lou
Pau Creixell
Rune Linding
P2860
P304
P356
10.1016/J.CELL.2015.08.057
P407
P577
2015-09-17T00:00:00Z