Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes.
about
T cell activation through the CD43 molecule leads to Vav tyrosine phosphorylation and mitogen-activated protein kinase pathway activationTSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentationSeveral different cell surface molecules control negative selection of medullary thymocytesWhen immunization leads to autoimmunity: chronic inflammation as a result of thymic and mucosal dysregulation in IL-2 knock-out mice.Organ-specific autoimmune disease: a deficiency of tolerogenic stimulationCostimulatory signals are required for induction of transcription factor Nur77 during negative selection of CD4(+)CD8(+) thymocytes.Cell migration and the control of post-natal T-cell lymphopoiesis in the thymus.Differences in the level of expression of class I major histocompatibility complex proteins on thymic epithelial and dendritic cells influence the decision of immature thymocytes between positive and negative selection.Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.Perinatal blockade of b7-1 and b7-2 inhibits clonal deletion of highly pathogenic autoreactive T cells.Receptor avidity and costimulation specify the intracellular Ca2+ signaling pattern in CD4(+)CD8(+) thymocytes.Quantitative impact of thymic clonal deletion on the T cell repertoire.T cell receptor (TCR)-induced death of immature CD4+CD8+ thymocytes by two distinct mechanisms differing in their requirement for CD28 costimulation: implications for negative selection in the thymus.The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytesThymocyte development is normal in CTLA-4-deficient miceA role for Ly108 in the induction of promyelocytic zinc finger transcription factor in developing thymocytesRequirements for selection of conventional and innate T lymphocyte lineages.Signals and pathways controlling regulatory T cells.The molecular jury: deciding whether immature thymocytes should live or die.Regulatory T-cell development and function are impaired in mice lacking membrane expression of full length intercellular adhesion molecule-1.Aging leads to disturbed homeostasis of memory phenotype CD8(+) cells.A monoclonal antibody against the extracellular domain of mouse and human epithelial V-like antigen 1 reveals a restricted expression pattern among CD4- CD8- thymocytes.Thymocyte selection: not by TCR alone.
P2860
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P2860
Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Differing roles for B7 and int ...... ative selection of thymocytes.
@en
type
label
Differing roles for B7 and int ...... ative selection of thymocytes.
@en
prefLabel
Differing roles for B7 and int ...... ative selection of thymocytes.
@en
P2093
P2860
P356
P1476
Differing roles for B7 and int ...... ative selection of thymocytes.
@en
P2093
P2860
P304
P356
10.1084/JEM.184.2.531
P407
P577
1996-08-01T00:00:00Z