An essential role for gp39, the ligand for CD40, in thymic selection.
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RORgamma t, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cellsCentral tolerance: learning self-control in the thymusSeveral different cell surface molecules control negative selection of medullary thymocytesThe timing of TCR alpha expression critically influences T cell development and selectionCD40 ligand-mediated interactions are involved in the generation of memory CD8(+) cytotoxic T lymphocytes (CTL) but are not required for the maintenance of CTL memory following virus infection.A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytesReview article: thymus organ cultures and T-cell receptor repertoire development.The role of the thymus in tolerance.Accelerated thymocyte maturation in IL-12Rβ2-deficient mice contributes to increased susceptibility to autoimmune inflammatory demyelinationPreformed CD40L is stored in Th1, Th2, Th17, and T follicular helper cells as well as CD4+ 8- thymocytes and invariant NKT cells but not in Treg cells.Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation.Generation of mice deficient for macrophage galactose- and N-acetylgalactosamine-specific lectin: limited role in lymphoid and erythroid homeostasis and evidence for multiple lectinsT cell-B cell thymic cross-talk: maintenance and function of thymic B cells requires cognate CD40-CD40 ligand interaction.Foxp3+ regulatory T cells promiscuously accept thymic signals critical for their developmentCostimulatory signals are required for induction of transcription factor Nur77 during negative selection of CD4(+)CD8(+) thymocytes.Resident B cells regulate thymic expression of myelin oligodendrocyte glycoprotein.T-helper cell tolerance to ubiquitous nuclear antigensTumor necrosis factor-related apoptosis-inducing ligand in T cell development: sensitivity of human thymocytesCross-linking of T-cell receptors on double-positive thymocytes induces a cytokine-mediated stromal activation process linked to cell deathDifferences in the level of expression of class I major histocompatibility complex proteins on thymic epithelial and dendritic cells influence the decision of immature thymocytes between positive and negative selection.CD8(+) T cells mediate CD40-independent maturation of dendritic cells in vivoThe JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytesClonal deletion of thymocytes can occur in the cortex with no involvement of the medullaThymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways.Molecular and genetic parameters defining T-cell clonal selection.TNF receptor family signaling in the development and functions of medullary thymic epithelial cells.Genetic basis of altered central tolerance and autoimmune diseases: a lesson from AIRE mutations.Alterations of the autoimmune regulator transcription factor and failure of central tolerance: APECED as a model.The hyper IgM syndromes.Inhibition of activation induced CD154 on CD4+ CD25- cells: a valid surrogate for human Treg suppressor function.The thymic stromal cell line MTSC4 induced thymocyte apoptosis in a non-MHC-restricted manner.CD40 expressed on human melanoma cells mediates T cell co-stimulation and tumor cell growth.CD40/CD40 ligand interactions in normal, reactive and malignant lympho-hematopoietic tissues.Molecular mimicry and T cell-mediated autoimmune disease.Abrogation of CD40-CD154 signaling impedes the homeostasis of thymic resident regulatory T cells by altering the levels of IL-2, but does not affect regulatory T cell development.Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes.CD27 cooperates with the pre-T cell receptor in the regulation of murine T cell development.Antigen compartmentation and T helper cell tolerance induction.A new mechanism of NK cell cytotoxicity activation: the CD40-CD40 ligand interaction.Thymic lymphoproliferative disease after successful correction of CD40 ligand deficiency by gene transfer in mice.
P2860
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P2860
An essential role for gp39, the ligand for CD40, in thymic selection.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
An essential role for gp39, the ligand for CD40, in thymic selection.
@ast
An essential role for gp39, the ligand for CD40, in thymic selection.
@en
type
label
An essential role for gp39, the ligand for CD40, in thymic selection.
@ast
An essential role for gp39, the ligand for CD40, in thymic selection.
@en
prefLabel
An essential role for gp39, the ligand for CD40, in thymic selection.
@ast
An essential role for gp39, the ligand for CD40, in thymic selection.
@en
P2093
P2860
P356
P1476
An essential role for gp39, the ligand for CD40, in thymic selection
@en
P2093
A Schoneveld
E Claassen
J A Ledbetter
R A Flavell
R J Noelle
P2860
P304
P356
10.1084/JEM.182.5.1377
P407
P577
1995-11-01T00:00:00Z