Targeting kynurenine aminotransferase II in psychiatric diseases: promising effects of an orally active enzyme inhibitor.
about
Continuous kynurenine administration during the prenatal period, but not during adolescence, causes learning and memory deficits in adult ratsKynurenine Pathway of Tryptophan Metabolism: Regulatory and Functional Aspects.Assessment of the Human Kynurenine Pathway: Comparisons and Clinical Implications of Ethnic and Gender Differences in Plasma Tryptophan, Kynurenine Metabolites, and Enzyme Expressions at Baseline and After Acute Tryptophan Loading and Depletionω-Amidase: an underappreciated, but important enzyme in L-glutamine and L-asparagine metabolism; relevance to sulfur and nitrogen metabolism, tumor biology and hyperammonemic diseases.Elevated kynurenine pathway metabolism during neurodevelopment: Implications for brain and behavior.Major developments in the design of inhibitors along the kynurenine pathway.The kynurenine pathway and the brain: Challenges, controversies and promises.Inhibitors of the kynurenine pathway as neurotherapeutics: a patent review (2012-2015).Kynurenines and Glutamate: Multiple Links and Therapeutic Implications.Kynurenic Acid in Schizophrenia: A Systematic Review and Meta-analysis.Tryptophan Metabolism in Rat Liver After Administration of Tryptophan, Kynurenine Metabolites, and Kynureninase Inhibitors.Distress intolerance, kynurenic acid, and schizophrenia.Exposure to Kynurenic Acid during Adolescence Increases Sign-Tracking and Impairs Long-Term Potentiation in Adulthood.Adaptive and Behavioral Changes in Kynurenine 3-Monooxygenase Knockout Mice: Relevance to Psychotic Disorders.Inhibition of human kynurenine aminotransferase isozymes by estrogen and its derivatives.Prenatal kynurenine exposure in rats: age-dependent changes in NMDA receptor expression and conditioned fear responding.Acute Kynurenine Challenge Disrupts Sleep-Wake Architecture and Impairs Contextual Memory in Adult Rats.Study of the Activity and Possible Mechanism of Action of a Reversible Inhibitor of Recombinant Human KAT-2: A Promising Lead in Neurodegenerative and Cognitive Disorders.Oral administration of a specific kynurenic acid synthesis (KAT II) inhibitor attenuates evoked glutamate release in rat prefrontal cortex.C-reactive protein is increased in schizophrenia but is not altered by antipsychotics: meta-analysis and implications.Improvement of kynurenine aminotransferase-II inhibitors guided by mimicking sulfate esters.
P2860
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P2860
Targeting kynurenine aminotransferase II in psychiatric diseases: promising effects of an orally active enzyme inhibitor.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Targeting kynurenine aminotran ...... rally active enzyme inhibitor.
@en
type
label
Targeting kynurenine aminotran ...... rally active enzyme inhibitor.
@en
prefLabel
Targeting kynurenine aminotran ...... rally active enzyme inhibitor.
@en
P2093
P2860
P356
P1476
Targeting kynurenine aminotran ...... rally active enzyme inhibitor.
@en
P2093
Ana Pocivavsek
Hui-Qiu Wu
John P Bruno
Masahiro Okuyama
Robert Schwarcz
Yasushi Kajii
P2860
P304
P356
10.1093/SCHBUL/SBT157
P407
P478
40 Suppl 2
P577
2014-03-01T00:00:00Z