Cyclin T1 and CDK9 T-loop phosphorylation are downregulated during establishment of HIV-1 latency in primary resting memory CD4+ T cells.
about
Roles of microRNAs and long-noncoding RNAs in human immunodeficiency virus replicationTranscriptional control of HIV latency: cellular signaling pathways, epigenetics, happenstance and the hope for a curePhosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytesAn in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patientsAn In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene ExpressionProteasome inhibitors act as bifunctional antagonists of human immunodeficiency virus type 1 latency and replication.Mechanisms of HIV Transcriptional Regulation by Drugs of Abuse.Cyclin-dependent kinase 9 may as a novel target in downregulating the atherosclerosis inflammation (Review).Epigenetic heterogeneity in HIV-1 latency establishment.Measuring glutathione redox potential of HIV-1-infected macrophages.ZASC1 stimulates HIV-1 transcription elongation by recruiting P-TEFb and TAT to the LTR promoter.Eradicating HIV-1 infection: seeking to clear a persistent pathogen.Subversion of Cell Cycle Regulatory Mechanisms by HIV.Modeling the Effects of Vorinostat In Vivo Reveals both Transient and Delayed HIV Transcriptional Activation and Minimal Killing of Latently Infected Cells.Cocaine promotes both initiation and elongation phase of HIV-1 transcription by activating NF-κB and MSK1 and inducing selective epigenetic modifications at HIV-1 LTRShort Communication: The Broad-Spectrum Histone Deacetylase Inhibitors Vorinostat and Panobinostat Activate Latent HIV in CD4(+) T Cells In Part Through Phosphorylation of the T-Loop of the CDK9 Subunit of P-TEFb.Elevated Plasma Viral Loads in Romidepsin-Treated Simian Immunodeficiency Virus-Infected Rhesus Macaques on Suppressive Combination Antiretroviral Therapy.The BET inhibitor OTX015 reactivates latent HIV-1 through P-TEFb.The effects of cocaine on HIV transcriptionReactivation of latent HIV-1 in central memory CD4⁺ T cells through TLR-1/2 stimulation.Regulation of CDK9 activity by phosphorylation and dephosphorylation.Cellular and molecular mechanisms involved in the establishment of HIV-1 latency.Reactivation of latent HIV: do all roads go through P-TEFb?T Cell Transcription Factors and Their Impact on HIV Expression.HIV-1 latency: an update of molecular mechanisms and therapeutic strategies.HIV-1 endocytosis in astrocytes: a kiss of death or survival of the fittest?HIV eradication: combinatorial approaches to activate latent viruses.Promising Role of Toll-Like Receptor 8 Agonist in Concert with Prostratin for Activation of Silent HIV.Cyclin-dependent kinases as therapeutic targets for HIV-1 infection.Short communication: SAHA (vorinostat) induces CDK9 Thr-186 (T-loop) phosphorylation in resting CD4+ T cells: implications for reactivation of latent HIV.Histone deacetylase inhibitors (HDACis) that release the positive transcription elongation factor b (P-TEFb) from its inhibitory complex also activate HIV transcription.The HIV-1 Tat protein: mechanism of action and target for HIV-1 cure strategies.HIV Provirus Stably Reproduces Parental Latent and Induced Transcription Phenotypes Regardless of the Chromosomal Integration Site.BET inhibitors RVX-208 and PFI-1 reactivate HIV-1 from latency.Proteomic Profiling of a Primary CD4+ T Cell Model of HIV-1 Latency Identifies Proteins Whose Differential Expression Correlates with Reactivation of Latent HIV-1.Molecular Control of HIV and SIV Latency.Tackling HIV Persistence: Pharmacological versus CRISPR-Based Shock Strategies.Long Noncoding RNA uc002yug.2 Activates HIV-1 Latency through Regulation of mRNA Levels of Various RUNX1 Isoforms and Increased Tat Expression.Cyclin-dependent kinase 7 (CDK7)-mediated phosphorylation of the CDK9 activation loop promotes P-TEFb assembly with Tat and proviral HIV reactivation.
P2860
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P2860
Cyclin T1 and CDK9 T-loop phosphorylation are downregulated during establishment of HIV-1 latency in primary resting memory CD4+ T cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Cyclin T1 and CDK9 T-loop phos ...... y resting memory CD4+ T cells.
@en
Cyclin T1 and CDK9 T-loop phos ...... y resting memory CD4+ T cells.
@nl
type
label
Cyclin T1 and CDK9 T-loop phos ...... y resting memory CD4+ T cells.
@en
Cyclin T1 and CDK9 T-loop phos ...... y resting memory CD4+ T cells.
@nl
prefLabel
Cyclin T1 and CDK9 T-loop phos ...... y resting memory CD4+ T cells.
@en
Cyclin T1 and CDK9 T-loop phos ...... y resting memory CD4+ T cells.
@nl
P2093
P2860
P356
P1433
P1476
Cyclin T1 and CDK9 T-loop phos ...... ry resting memory CD4+ T cells
@en
P2093
Marylinda Famiglietti
Sona Budhiraja
Vicente Planelles
P2860
P304
P356
10.1128/JVI.02413-12
P407
P577
2012-11-14T00:00:00Z