A salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter.
about
X-ray structures and mechanism of the human serotonin transporter.A Highly Conserved Salt Bridge Stabilizes the Kinked Conformation of β2,3-Sheet Essential for Channel Function of P2X4 ReceptorsGenetically encoded photocrosslinkers locate the high-affinity binding site of antidepressant drugs in the human serotonin transporter.Direct PIP2 binding mediates stable oligomer formation of the serotonin transporterDopamine Transporter Amino and Carboxyl Termini Synergistically Contribute to Substrate and Inhibitor Affinities.Pharmacological Chaperones of the Dopamine Transporter Rescue Dopamine Transporter Deficiency Syndrome Mutations in Heterologous Cells.Functional Rescue of a Misfolded Drosophila melanogaster Dopamine Transporter Mutant Associated with a Sleepless Phenotype by Pharmacological Chaperones.Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates.The N Terminus Specifies the Switch between Transport Modes of the Human Serotonin Transporter.An unfolding story: Small molecules remedy misfolded monoamine transporters.Pharmacochaperoning in a Drosophila model system rescues human dopamine transporter variants associated with infantile/juvenile parkinsonism.Relax, Cool Down and Scaffold: How to Restore Surface Expression of Folding-Deficient Mutant GPCRs and SLC6 Transporters.SLC6 Transporter Folding Diseases and Pharmacochaperoning.Structural basis for recognition of diverse antidepressants by the human serotonin transporter.
P2860
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P2860
A salt bridge linking the first intracellular loop with the C terminus facilitates the folding of the serotonin transporter.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
A salt bridge linking the firs ...... of the serotonin transporter.
@en
A salt bridge linking the firs ...... of the serotonin transporter.
@nl
type
label
A salt bridge linking the firs ...... of the serotonin transporter.
@en
A salt bridge linking the firs ...... of the serotonin transporter.
@nl
prefLabel
A salt bridge linking the firs ...... of the serotonin transporter.
@en
A salt bridge linking the firs ...... of the serotonin transporter.
@nl
P2093
P2860
P50
P356
P1476
A salt bridge linking the firs ...... of the serotonin transporter.
@en
P2093
Ali El-Kasaby
Benedikt M Simbrunner
Cornelia Häusler
Florian Koban
P2860
P304
13263-13278
P356
10.1074/JBC.M115.641357
P407
P577
2015-04-13T00:00:00Z