about
Synthesis of highly substituted allenylsilanes by alkylidenation of silylketenes.Evaluating New Chemistry to Drive Molecular Discovery: Fit for Purpose?A divergent synthetic approach to diverse molecular scaffolds: assessment of lead-likeness using LLAMA, an open-access computational tool.A unified lead-oriented synthesis of over fifty molecular scaffolds.Design, synthesis and decoration of molecular scaffolds for exploitation in the production of alkaloid-like libraries.Aminomethylhydroxylation of alkenes: Exploitation in the synthesis of scaffolds for small molecule libraries.Recent advances and applications of iridium-catalysed asymmetric allylic substitution.Towards the realisation of lead-oriented synthesis.Copper catalysed Ullmann type chemistry: from mechanistic aspects to modern development.Total synthesis of the indolizidine alkaloid tashiromine.A convergent, umpoled synthesis of 2-(1-amidoalkyl)pyridines.Selective amine cross-coupling using iridium-catalyzed "borrowing hydrogen" methodology.Synthesis and bio-assay of RCM-derived Bowman-Birk inhibitor analogues.Reagent-controlled stereoselective synthesis of lignan-related tetrahydrofurans.Total synthesis of rapamycin.Chiral N-heterocyclic carbene ligands for asymmetric catalytic oxindole synthesis.Convenient synthesis of 3-alkoxy-3-aryloxindoles by intramolecular arylation of mandelic amides.Picolinamides as effective ligands for copper-catalysed aryl ether formation: structure-activity relationships, substrate scope and mechanistic investigations.A systematic approach to diverse, lead-like scaffolds from α,α-disubstituted amino acids.Alkene hydroboration: hot intermediates that react while they are cooling.Significance of nonstatistical dynamics in organic reaction mechanisms: time-dependent stereoselectivity in cyclopentyne-alkene cycloadditions.Direct Synthesis of N-Alkyl Arylglycines by Organocatalytic Asymmetric Transfer Hydrogenation of N-Alkyl Aryl Imino Esters.A biosynthesis-inspired approach to over twenty diverse natural product-like scaffolds.Rhodium(III)-catalyzed C-H activation/annulation with vinyl esters as an acetylene equivalent.A convergent rhodium-catalysed asymmetric synthesis of tetrahydroquinolines.Catalyst control in sequential asymmetric allylic substitution: stereodivergent access to N,N-diprotected unnatural amino acids.Synthesis of benzazoles by hydrogen-transfer catalysis.Total synthesis of the immunosuppressants myriocin and 2-epi-myriocin.Convergent, regiospecific synthesis of quinolines from o-aminophenylboronates.Facile and general synthesis of quaternary 3-aminooxindoles.Catalytic aza-Wittig cyclizations for heteroaromatic synthesis.Isotopic labeling for determination of enantiomeric purity by 2H NMR spectroscopy.Electrophile-directed diastereoselective alkylation of prochiral enediolates.Efficient asymmetric synthesis of quaternary (E)-vinylglycines by deconjugative alkylation of dehydroamino acids.Deconjugation of dehydroamino acids: stereoselective synthesis of racemic (E)-vinylglycines.Stereocontrolled assembly of tetrasubstituted tetrahydrofurans: a concise synthesis of virgatusin.A novel, stereoselective and convergent synthesis of aryltetralins.A concise, convergent total synthesis of monocerin.Exploitation of the Ugi–Joullié Reaction in the Synthesis of Libraries of Drug-Like Bicyclic HydantoinsTranslation of innovative chemistry into screening libraries: an exemplar partnership from the European Lead Factory
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Stephen P. Marsden
@ast
Stephen P. Marsden
@en
Stephen P. Marsden
@es
Stephen P. Marsden
@nl
Stephen P. Marsden
@sl
type
label
Stephen P. Marsden
@ast
Stephen P. Marsden
@en
Stephen P. Marsden
@es
Stephen P. Marsden
@nl
Stephen P. Marsden
@sl
prefLabel
Stephen P. Marsden
@ast
Stephen P. Marsden
@en
Stephen P. Marsden
@es
Stephen P. Marsden
@nl
Stephen P. Marsden
@sl
P185
P1053
A-1960-2016
P106
P1153
7006832327
P1416
P2031
1994-01-01T00:00:00Z
P21
P31
P3829
P496
0000-0002-2723-8954