Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin.
about
Cyanobacterial Polyketide Synthase Docking Domains: A Tool for Engineering Natural Product BiosynthesisArchitecture of the polyketide synthase module: surprises from electron cryo-microscopyPolyketide intermediate mimics as probes for revealing cryptic stereochemistry of ketoreductase domains.Structural basis of substrate specificity and regiochemistry in the MycF/TylF family of sugar O-methyltransferases.Evolution of Efficient Modular Polyketide Synthases by Homologous RecombinationTwelve-membered macrolactones: privileged scaffolds for the development of new therapeutics.Resistance to ketolide antibiotics by coordinated expression of rRNA methyltransferases in a bacterial producer of natural ketolides.Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering.Investigating the reactivities of a polyketide synthase module through fluorescent click chemistry.Uncovering the structures of modular polyketide synthases.Stereocontrolled Total Synthesis of (-)-Stemaphylline.Biochemical and Structural Characterization of MycCI, a Versatile P450 Biocatalyst from the Mycinamicin Biosynthetic Pathway.Structural rearrangements of a polyketide synthase module during its catalytic cycle.Structure of a modular polyketide synthase.Substrate controlled divergence in polyketide synthase catalysis.Identification of a Thioesterase Bottleneck in the Pikromycin Pathway through Full-Module Processing of Unnatural Pentaketides.Co-produced natural ketolides methymycin and pikromycin inhibit bacterial growth by preventing synthesis of a limited number of proteins.Chemoenzymatic Total Synthesis and Structural Diversification of Tylactone-Based Macrolide Antibiotics through Late-Stage Polyketide Assembly, Tailoring, and C-H Functionalization.
P2860
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P2860
Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Biocatalytic synthesis of pikr ...... ethymycin, and ketomethymycin.
@en
Biocatalytic synthesis of pikr ...... ethymycin, and ketomethymycin.
@nl
type
label
Biocatalytic synthesis of pikr ...... ethymycin, and ketomethymycin.
@en
Biocatalytic synthesis of pikr ...... ethymycin, and ketomethymycin.
@nl
prefLabel
Biocatalytic synthesis of pikr ...... ethymycin, and ketomethymycin.
@en
Biocatalytic synthesis of pikr ...... ethymycin, and ketomethymycin.
@nl
P2093
P2860
P921
P356
P1476
Biocatalytic synthesis of pikr ...... ethymycin, and ketomethymycin.
@en
P2093
Alison R H Narayan
Christopher M Rath
David H Sherman
Eli B Eisman
Jeffrey D Kittendorf
Jonathan D Mortison
Yeo Joon Yoon
P2860
P304
11232-11238
P356
10.1021/JA404134F
P407
P577
2013-07-18T00:00:00Z