Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development.
about
Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signallingChromatin targeting drugs in cancer and immunityDual retrovirus integration tagging: identification of new signaling molecules Fiz1 and Hipk2 that are involved in the IL-7 signaling pathway in B lymphoblastic lymphomasATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytesRegulatory T cells: mechanisms of differentiation and functionNovel mechanism of tumor suppression by polarity gene discs large 1 (DLG1) revealed in a murine model of pediatric B-ALL.Epigenetic control of immunityCritical roles for c-Myb in lymphoid priming and early B-cell developmentIntegrated genetic approaches identify the molecular mechanisms of Sox4 in early B-cell development: intricate roles for RAG1/2 and CK1ε.PDK1 regulates B cell differentiation and homeostasis.Flt3 signaling regulates the proliferation, survival, and maintenance of multipotent hematopoietic progenitors that generate B cell precursors.BCL6 is critical for the development of a diverse primary B cell repertoire.Withacnistin inhibits recruitment of STAT3 and STAT5 to growth factor and cytokine receptors and induces regression of breast tumoursEpigenetic regulation of antigen receptor gene rearrangementB lymphocyte lineage specification, commitment and epigenetic control of transcription by early B cell factor 1.E proteins and the regulation of early lymphocyte developmentTransition pattern and mechanism of B-lymphocyte precursors in regenerated mouse bone marrow after subtotal body irradiationThe NAMPT promoter is regulated by mechanical stress, signal transducer and activator of transcription 5, and acute respiratory distress syndrome-associated genetic variants.Comprehensive meta-analysis of Signal Transducers and Activators of Transcription (STAT) genomic binding patterns discerns cell-specific cis-regulatory modulesFyn kinase is required for optimal humoral responses.The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrowIL-7R expression and IL-7 signaling confer a distinct phenotype on developing human B-lineage cells.Defective hematopoietic stem cell and lymphoid progenitor development in the Ts65Dn mouse model of Down syndrome: potential role of oxidative stress.IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection.Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia.RAG-induced DNA double-strand breaks signal through Pim2 to promote pre-B cell survival and limit proliferation.SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation.Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemiaVprBP Is Required for Efficient Editing and Selection of Igκ+ B Cells, but Is Dispensable for Igλ+ and Marginal Zone B Cell Maturation and Selection.CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability.Cell-type-specific expression of STAT transcription factors in tissue samples from patients with lymphocytic thyroiditis.The Zinc-finger protein ASCIZ regulates B cell development via DYNLL1 and Bim.JAK and STAT signaling molecules in immunoregulation and immune-mediated disease.Integrated signaling in developing lymphocytes: the role of DNA damage responses.The ataxia telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondary Vκ-to-Jκ rearrangementsSox4 is required for the survival of pro-B cells.The BH3-only protein BIM contributes to late-stage involution in the mouse mammary gland.Cutting edge: cell-autonomous control of IL-7 response revealed in a novel stage of precursor B cellsLymphocyte development: integration of DNA damage response signaling.
P2860
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P2860
Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Role of STAT5 in controlling c ...... during pro-B cell development.
@en
Role of STAT5 in controlling c ...... during pro-B cell development.
@nl
type
label
Role of STAT5 in controlling c ...... during pro-B cell development.
@en
Role of STAT5 in controlling c ...... during pro-B cell development.
@nl
prefLabel
Role of STAT5 in controlling c ...... during pro-B cell development.
@en
Role of STAT5 in controlling c ...... during pro-B cell development.
@nl
P2093
P2860
P50
P356
P1433
P1476
Role of STAT5 in controlling c ...... during pro-B cell development.
@en
P2093
Maria Novatchkova
Shane McManus
Stephen Malin
P2860
P2888
P304
P356
10.1038/NI.1827
P407
P577
2009-11-29T00:00:00Z
P5875
P6179
1050743912