Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation
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The tumor suppressor hTid1 inhibits STAT5b activity via functional interactionIdentification of a cytokine-induced antiapoptotic molecule anamorsin essential for definitive hematopoiesisInterleukin 3-dependent activation of DREAM is involved in transcriptional silencing of the apoptotic Hrk gene in hematopoietic progenitor cells.Prolactin signaling and Stat5: going their own separate ways?Nuclear factor kappaB-dependent gene expression profiling of Hodgkin's disease tumor cells, pathogenetic significance, and link to constitutive signal transducer and activator of transcription 5a activityTranscription elongation factor S-II is required for definitive hematopoiesis.The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells.GM-CSF induces STAT5 binding at epigenetic regulatory sites within the Csf2 promoter of non-obese diabetic (NOD) mouse myeloid cellsNonobese diabetic mouse congenic analysis reveals chromosome 11 locus contributing to diabetes susceptibility, macrophage STAT5 dysfunction, and granulocyte-macrophage colony-stimulating factor overproductionThe transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis.Single-cell STAT5 signal transduction profiling in normal and leukemic stem and progenitor cell populations reveals highly distinct cytokine responsesSTAT5 is an ambivalent regulator of neutrophil homeostasisStrain-dependent host transcriptional responses to Toxoplasma infection are largely conserved in mammalian and avian hosts.The different functions of Stat5 and chromatin alteration through Stat5 proteinsGain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lungSTAT5 and Oct-1 form a stable complex that modulates cyclin D1 expression.STAT5 requires the N-domain to maintain hematopoietic stem cell repopulating function and appropriate lymphoid-myeloid lineage output.Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis.Constitutive activation of STAT5A promotes human hematopoietic stem cell self-renewal and erythroid differentiation.Granulocyte/macrophage colony-stimulating factor and accessory cells modulate radioprotection by purified hematopoietic cellsProduction of interleukin‑4 in CD133+ cervical cancer stem cells promotes resistance to apoptosis and initiates tumor growthSignal transduction activator of transcription 5 (STAT5) dysfunction in autoimmune monocytes and macrophagesSignal transduction inhibition of APCs diminishes th17 and Th1 responses in experimental autoimmune encephalomyelitisSrc-family kinases in the development and therapy of Philadelphia chromosome-positive chronic myeloid leukemia and acute lymphoblastic leukemia.Biology and significance of the JAK/STAT signalling pathways.M-CSF elevates c-Fos and phospho-C/EBPalpha(S21) via ERK whereas G-CSF stimulates SHP2 phosphorylation in marrow progenitors to contribute to myeloid lineage specification.The combination effect of homoharringtonine and ibrutinib on FLT3-ITD mutant acute myeloid leukemia.STAT5-mediated self-renewal of normal hematopoietic and leukemic stem cells.Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 geneTissue-microarray based immunohistochemical analysis of survival pathways in nodular sclerosing classical Hodgkin lymphoma as compared with Non-Hodgkin's lymphoma.Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter.Src family kinases interfere with dimerization of STAT5A through a phosphotyrosine-SH2 domain interaction.Type I diabetes-associated tolerogenic properties of interleukin-2.Erythroid progenitor renewal versus differentiation: genetic evidence for cell autonomous, essential functions of EpoR, Stat5 and the GR.Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia.Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development.Ectopic expression of C/EBPalpha and ID1 is sufficient to restore defective neutrophil development in low-risk myelodysplasiaSTAT5 signaling is required for the efficient induction and maintenance of CML in mice.Raf-1 antagonizes erythroid differentiation by restraining caspase activation.Transcriptional Regulation of Emergency Granulopoiesis in Leukemia.
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P2860
Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation
description
2000 nî lūn-bûn
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2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
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2000年論文
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2000年論文
@zh-tw
2000年论文
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name
Antiapoptotic activity of Stat ...... ges of myeloid differentiation
@ast
Antiapoptotic activity of Stat ...... ges of myeloid differentiation
@en
Antiapoptotic activity of Stat ...... ges of myeloid differentiation
@en-gb
Antiapoptotic activity of Stat ...... ges of myeloid differentiation
@nl
type
label
Antiapoptotic activity of Stat ...... ges of myeloid differentiation
@ast
Antiapoptotic activity of Stat ...... ges of myeloid differentiation
@en
Antiapoptotic activity of Stat ...... ges of myeloid differentiation
@en-gb
Antiapoptotic activity of Stat ...... ges of myeloid differentiation
@nl
prefLabel
Antiapoptotic activity of Stat ...... ges of myeloid differentiation
@ast
Antiapoptotic activity of Stat ...... ges of myeloid differentiation
@en
Antiapoptotic activity of Stat ...... ges of myeloid differentiation
@en-gb
Antiapoptotic activity of Stat ...... ges of myeloid differentiation
@nl
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Antiapoptotic activity of Stat ...... ges of myeloid differentiation
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2000-01-01T00:00:00Z