Use of collateral sensitivity networks to design drug cycling protocols that avoid resistance development.
about
Precision or Personalized Medicine for Cancer Chemotherapy: Is there a Role for Herbal MedicineSpatiotemporal microbial evolution on antibiotic landscapesCosts of antibiotic resistance - separating trait effects and selective effectsCompounds that select against the tetracycline-resistance efflux pumpUsing a sequential regimen to eliminate bacteria at sublethal antibiotic dosagesSteering Evolution with Sequential Therapy to Prevent the Emergence of Bacterial Antibiotic ResistanceQuantifying the Determinants of Evolutionary Dynamics Leading to Drug ResistanceMolecular Mechanisms for Drug Hypersensitivity Induced by the Malaria Parasite's Chloroquine Resistance TransporterMarkov Networks of Collateral Resistance: National Antimicrobial Resistance Monitoring System Surveillance Results from Escherichia coli Isolates, 2004-2012Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic EfficacyAntimicrobial resistance in humans, livestock and the wider environmentEndless Resistance. Endless Antibiotics?Reconstruction of the metabolic network of Pseudomonas aeruginosa to interrogate virulence factor synthesis.Miniaturized plate readers for low-cost, high-throughput phenotypic screening.The yin and yang of bacterial resilience in the human gut microbiota.Modeling Tumor Clonal Evolution for Drug Combinations DesignAdaptive Laboratory Evolution of Antibiotic Resistance Using Different Selection Regimes Lead to Similar Phenotypes and Genotypes.Collateral sensitivity networks reveal evolutionary instability and novel treatment strategies in ALK mutated non-small cell lung cancerTargeting the Achilles heel of multidrug-resistant cancer by exploiting the fitness cost of resistance.Time-programmable drug dosing allows the manipulation, suppression and reversal of antibiotic drug resistance in vitroMultidrug evolutionary strategies to reverse antibiotic resistance.Alternating antibiotic treatments constrain evolutionary paths to multidrug resistancePrediction of antibiotic resistance by gene expression profiles.Role of pleiotropy during adaptation of TEM-1 β-lactamase to two novel antibiotics.One cannot rule them all: Are bacterial toxins-antitoxins druggable?Prediction of resistance development against drug combinations by collateral responses to component drugs.Combination Effects of Antimicrobial Peptides.Synergistic, collaterally sensitive β-lactam combinations suppress resistance in MRSA.A pivot mutation impedes reverse evolution across an adaptive landscape for drug resistance in Plasmodium vivaxMacrophage adaptation leads to parallel evolution of genetically diverse Escherichia coli small-colony variants with increased fitness in vivo and antibiotic collateral sensitivity.A Hybrid Drug Limits Resistance by Evading the Action of the Multiple Antibiotic Resistance Pathway.Immune-system-dependent anti-tumor activity of a plant-derived polyphenol rich fraction in a melanoma mouse model.Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution.Effect of antibiotics on bacterial populations: a multi-hierachical selection process.Combinatorial strategies for combating invasive fungal infections.Collective antibiotic resistance: mechanisms and implications.Mechanisms and therapeutic potential of inhibiting drug efflux transporters.Fighting antibiotic resistance in the intensive care unit using antibiotics.Collateral sensitivity of antibiotic-resistant microbes.Fighting microbial drug resistance: a primer on the role of evolutionary biology in public health
P2860
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P2860
Use of collateral sensitivity networks to design drug cycling protocols that avoid resistance development.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Use of collateral sensitivity ...... avoid resistance development.
@en
Use of collateral sensitivity ...... avoid resistance development.
@nl
type
label
Use of collateral sensitivity ...... avoid resistance development.
@en
Use of collateral sensitivity ...... avoid resistance development.
@nl
prefLabel
Use of collateral sensitivity ...... avoid resistance development.
@en
Use of collateral sensitivity ...... avoid resistance development.
@nl
P2860
P1476
Use of collateral sensitivity ...... t avoid resistance development
@en
P2093
Morten O A Sommer
P2860
P304
P356
10.1126/SCITRANSLMED.3006609
P407
P50
P577
2013-09-01T00:00:00Z