Elevated levels of tryparedoxin peroxidase in antimony unresponsive Leishmania donovani field isolates.
about
Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistanceMolecular mechanisms of drug resistance in natural Leishmania populations vary with genetic backgroundStage-dependent expression and up-regulation of trypanothione synthetase in amphotericin B resistant Leishmania donovaniSpecies-specific antimonial sensitivity in Leishmania is driven by post-transcriptional regulation of AQP1A Multiplatform Metabolomic Approach to the Basis of Antimonial Action and Resistance in Leishmania infantumPolyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilitiesDrug resistance in eukaryotic microorganisms.Antimony transport mechanisms in resistant leishmania parasites.Leishmania amazonensis amastigotes highly express a tryparedoxin peroxidase isoform that increases parasite resistance to macrophage antimicrobial defenses and fosters parasite virulence.Visceral leishmaniasis and arsenic: an ancient poison contributing to antimonial treatment failure in the Indian subcontinent?Heterogeneity of molecular resistance patterns in antimony-resistant field isolates of Leishmania species from the western Mediterranean area.Functional analysis of cytosolic tryparedoxin peroxidase in antimony-resistant and -susceptible Leishmania braziliensis and Leishmania infantum lines.Regulation of Leishmania (L.) amazonensis protein expression by host T cell dependent responses: differential expression of oligopeptidase B, tryparedoxin peroxidase and HSP70 isoforms in amastigotes isolated from BALB/c and BALB/c nude mice.Use of antimony in the treatment of leishmaniasis: current status and future directions.Antimony resistance in leishmania, focusing on experimental research.Genome-wide SNP and microsatellite variation illuminate population-level epidemiology in the Leishmania donovani species complex.Peroxiredoxins in parasites.Deciphering the interplay between cysteine synthase and thiol cascade proteins in modulating Amphotericin B resistance and survival of Leishmania donovani under oxidative stress.Leishmania antimony resistance: what we know what we can learn from the field.Drug-resistant microorganisms with a higher fitness--can medicines boost pathogens?Tolerance to drug-induced cell death favours the acquisition of multidrug resistance in Leishmania.A Telomeric Cluster of Antimony Resistance Genes on Chromosome 34 of Leishmania infantum.The overexpression of genes of thiol metabolism contribute to drug resistance in clinical isolates of visceral leishmaniasis (kala azar) in India.Downregulation of mitogen-activated protein kinase 1 of Leishmania donovani field isolates is associated with antimony resistance.Expression Analysis of Multiple Genes May Involve in Antimony Resistance among Leishmania major Clinical Isolates from Fars Province, Central Iran.Phosphoproteomic analysis of wild-type and antimony-resistant Leishmania braziliensis lines by 2D-DIGE technology.Decreased antimony uptake and overexpression of genes of thiol metabolism are associated with drug resistance in a canine isolate of Leishmania infantum.Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation.Quantitative proteomic analysis of amastigotes from Leishmania (L.) amazonensis LV79 and PH8 strains reveals molecular traits associated with the virulence phenotype.Aldo-keto reductase and alcohol dehydrogenase contribute to benznidazole natural resistance in Trypanosoma cruzi.Functional Involvement of Leishmania donovani Tryparedoxin Peroxidases during Infection and Drug Treatment.Drug target validation of the trypanothione pathway enzymes through metabolic modelling.Characterisation of a Putative Glutamate 5- Kinase from Leishmania donovani.Comparative transcript expression analysis of miltefosine-sensitive and miltefosine-resistant Leishmania donovaniThiol Peroxidases of Trypanosomatids
P2860
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P2860
Elevated levels of tryparedoxin peroxidase in antimony unresponsive Leishmania donovani field isolates.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Elevated levels of tryparedoxi ...... mania donovani field isolates.
@en
Elevated levels of tryparedoxi ...... mania donovani field isolates.
@nl
type
label
Elevated levels of tryparedoxi ...... mania donovani field isolates.
@en
Elevated levels of tryparedoxi ...... mania donovani field isolates.
@nl
prefLabel
Elevated levels of tryparedoxi ...... mania donovani field isolates.
@en
Elevated levels of tryparedoxi ...... mania donovani field isolates.
@nl
P2093
P2860
P50
P921
P1476
Elevated levels of tryparedoxi ...... mania donovani field isolates.
@en
P2093
Goutam Mandal
Mitali Chatterjee
Neeloo Singh
P2860
P304
P356
10.1016/J.MOLBIOPARA.2010.05.015
P577
2010-05-27T00:00:00Z