about
Aurora B regulates MCAK at the mitotic centromereTIP150 interacts with and targets MCAK at the microtubule plus endsThe kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignmentA standardized kinesin nomenclatureMCAK associates with the tips of polymerizing microtubulesThe kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells.Divergent microtubule assembly rates after short- versus long-term loss of end-modulating kinesins.Cooperation of the Dam1 and Ndc80 kinetochore complexes enhances microtubule coupling and is regulated by aurora B.MCAK, a Kin I kinesin, increases the catastrophe frequency of steady-state HeLa cell microtubules in an ATP-dependent manner in vitroKinesin-2 is a motor for late endosomes and lysosomesTubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends.The tetrameric kinesin Kif25 suppresses pre-mitotic centrosome separation to establish proper spindle orientation.The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion.Phosphoregulation and depolymerization-driven movement of the Dam1 complex do not require ring formation.Catalysis of the microtubule on-rate is the major parameter regulating the depolymerase activity of MCAK.A tethering mechanism controls the processivity and kinetochore-microtubule plus-end enrichment of the kinesin-8 Kif18A.Oxidative stress decreases microtubule growth and stability in ventricular myocytesA perikinetochoric ring defined by MCAK and Aurora-B as a novel centromere domain.MCAK is present at centromeres, midspindle and chiasmata and involved in silencing of the spindle assembly checkpoint in mammalian oocytes.Microtubule length control, a team sport?In vitro and in vivo analysis of microtubule-destabilizing kinesinsLong astral microtubules uncouple mitotic spindles from the cytokinetic furrowMip1 associates with both the Mps1 kinase and actin, and is required for cell cortex stability and anaphase spindle positioning.Nucleotide exchange in dimeric MCAK induces longitudinal and lateral stress at microtubule ends to support depolymerization.Breathing down the neck of Unc104.AKAP220 protein organizes signaling elements that impact cell migration.Mitosis, microtubule dynamics and the evolution of kinesins.Mitotic centromere-associated kinesin (MCAK): a potential cancer drug target.The mechanism, function and regulation of depolymerizing kinesins during mitosis.Kif18A and chromokinesins confine centromere movements via microtubule growth suppression and spatial control of kinetochore tensionA mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells.The distribution of cytoplasmic microtubules throughout the cell cycle of the centric diatom Stephanopyxis turris: their role in nuclear migration and positioning the mitotic spindle during cytokinesis.Rings, bracelets, sleeves, and chevrons: new structures of kinetochore proteinsA new model for binding of kinesin 13 to curved microtubule protofilamentsReconstitution and functional analysis of kinetochore subcomplexes.ST-11: A New Brain-Penetrant Microtubule-Destabilizing Agent with Therapeutic Potential for Glioblastoma Multiforme.Molecular insight into the regulation and function of MCAK.Rapid measurement of mitotic spindle orientation in cultured mammalian cells.Mass spec studio for integrative structural biology.Roles for focal adhesion kinase (FAK) in blastomere abscission and vesicle trafficking during cleavage in the sea urchin embryo.
P50
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P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Linda Wordeman
@ast
Linda Wordeman
@en
Linda Wordeman
@es
Linda Wordeman
@nl
Linda Wordeman
@sl
type
label
Linda Wordeman
@ast
Linda Wordeman
@en
Linda Wordeman
@es
Linda Wordeman
@nl
Linda Wordeman
@sl
prefLabel
Linda Wordeman
@ast
Linda Wordeman
@en
Linda Wordeman
@es
Linda Wordeman
@nl
Linda Wordeman
@sl
P106
P21
P31
P496
0000-0002-9444-0650