Sequence determinants of E2-E6AP binding affinity and specificity.
about
The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysinesMolecular basis of Pirh2-mediated p53 ubiquitylationCrystal structure of SopA, a Salmonella effector protein mimicking a eukaryotic ubiquitin ligaseStructural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8’s E1 † ‡Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligasesInsights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L ComplexBiochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function ScreenMechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3E2s: structurally economical and functionally repleteEpigenetic regulation of UBE3A and roles in human neurodevelopmental disorders.Bi-directional SIFT predicts a subset of activating mutations.Orthogonal ubiquitin transfer through engineered E1-E2 cascades for protein ubiquitinationRigorous assessment and integration of the sequence and structure based features to predict hot spots.Peptide and small molecule inhibitors of HECT-type ubiquitin ligasesHuman proteome-scale structural modeling of E2-E3 interactions exploiting interface motifs.Catalytically Important Residues of E6AP Ubiquitin Ligase Identified Using Acid-Cleavable Photo-Cross-LinkersE6AP/UBE3A ubiquitin ligase harbors two E2~ubiquitin binding sites.Polyubiquitination by HECT E3s and the determinants of chain type specificity.Dynamic interactions of proteins in complex networks: identifying the complete set of interacting E2s for functional investigation of E3-dependent protein ubiquitination.A conformational switch regulates the ubiquitin ligase HUWE1.UbFluor: A Mechanism-Based Probe for HECT E3 Ligases.UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons.Phosphorylation of the E3 ubiquitin protein ligase ITCH diminishes binding to its cognate E2 ubiquitin ligase.In silico modeling of the cryptic E2∼ubiquitin-binding site of E6-associated protein (E6AP)/UBE3A reveals the mechanism of polyubiquitin chain assembly.The mechanism of neural precursor cell expressed developmentally down-regulated 4-2 (Nedd4-2)/NEDD4L-catalyzed polyubiquitin chain assembly.
P2860
Q24294518-319F9FA5-6991-4747-84B1-38972DA8FFCFQ24319435-BC1DC06E-69AE-487F-9998-B0917E46EAB2Q27649240-2F1E9633-AEC9-42B4-BC07-C600FA1488BEQ27651318-4932D868-65D0-443D-963A-1B68DDB97A47Q27652850-4A0718B7-7DA8-4FB0-B7C1-F1ABDD285CEDQ27658921-74543F96-8CFC-42EA-BC80-E44D9BA52448Q27665390-3883ACE1-97B7-4D6B-9422-2166DB9BAD6DQ27678481-0497A55A-D1B0-446C-8BBC-BD706A87C6DFQ28067393-12096D38-E95C-4A1C-95CC-959766CB1964Q28301074-14978563-F726-4DD4-88EC-3872F3B90DF3Q30373162-4F809079-E11A-4CC9-A841-6623839F29C2Q33518531-E0F5F278-2251-4AD8-9D6C-CDC905916151Q33924565-55B1638F-C603-4007-987C-C4163DAD6CE3Q33974356-D14BBCBB-9981-457C-85E3-2EA67CE96D9FQ34601308-4D270D4C-2771-499D-90C2-91E9A79F4D95Q35774953-62B2A664-B145-46CF-BE5C-75F806325AA9Q35925045-7670A6F9-77B3-41AA-9364-6B4E5D04993DQ36760286-B642CFBA-6F18-4235-9924-4B836FFFA8D5Q37233382-180AD7C5-A5DE-4356-BA39-8858726501B4Q37588018-3C8DEA60-F4F1-4C2E-BB3B-F18C90325880Q42321543-E6349AAB-8855-41A0-AD88-E483464AAFFCQ42395323-EE3DBF56-EB99-4BBB-A029-F881BDF05030Q46481974-DE72FE3E-F586-4387-8219-0A41CEFA4F59Q47322523-4776F4E1-7F3E-4F0A-8BFF-7D32E6717193Q47682400-AF72161A-2E59-4F5D-9CFB-131D0F168A22Q47709454-3B9A03FF-F41F-4E75-8386-4B34A5749660
P2860
Sequence determinants of E2-E6AP binding affinity and specificity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Sequence determinants of E2-E6AP binding affinity and specificity.
@en
Sequence determinants of E2-E6AP binding affinity and specificity.
@nl
type
label
Sequence determinants of E2-E6AP binding affinity and specificity.
@en
Sequence determinants of E2-E6AP binding affinity and specificity.
@nl
prefLabel
Sequence determinants of E2-E6AP binding affinity and specificity.
@en
Sequence determinants of E2-E6AP binding affinity and specificity.
@nl
P2860
P1476
Sequence determinants of E2-E6AP binding affinity and specificity.
@en
P2093
Ziad M Eletr
P2860
P304
P356
10.1016/J.JMB.2007.03.026
P407
P577
2007-03-19T00:00:00Z