Polyubiquitination by HECT E3s and the determinants of chain type specificity.
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LUBAC synthesizes linear ubiquitin chains via a thioester intermediateThe E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysinesOTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysisStructure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of NeuroprotectionHECT and RING finger families of E3 ubiquitin ligases at a glanceUbc13: the Lys63 ubiquitin chain building machineHeterotrimeric G Protein-coupled Receptor Signaling in Yeast Mating Pheromone ResponseUbiquitin in the immune systemInsights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L ComplexStructure of the HECT:ubiquitin complex and its role in ubiquitin chain elongationStructure and function of a HECT domain ubiquitin-binding siteStructure of the HECT C-lobe of the UBR5 E3 ubiquitin ligaseA Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function ScreenStructural Insights into the Conformation and Oligomerization of E2∼Ubiquitin ConjugatesMechanism of ubiquitin ligation and lysine prioritization by a HECT E3Rsp5 ubiquitin ligase is required for protein trafficking in Saccharomyces cerevisiae COPI mutants.The essential Ubc4/Ubc5 function in yeast is HECT E3-dependent, and RING E3-dependent pathways require only monoubiquitin transfer by Ubc4.Sna3 is an Rsp5 adaptor protein that relies on ubiquitination for its MVB sortingDefective in mitotic arrest 1 (Dma1) ubiquitin ligase controls G1 cyclin degradation.Specific α-arrestins negatively regulate Saccharomyces cerevisiae pheromone response by down-modulating the G-protein-coupled receptor Ste2.Rsp5/Nedd4 is the main ubiquitin ligase that targets cytosolic misfolded proteins following heat stress.A perturbed ubiquitin landscape distinguishes between ubiquitin in trafficking and in proteolysis.A mechanism for protein monoubiquitination dependent on a trans-acting ubiquitin-binding domain.Identification of an unconventional E3 binding surface on the UbcH5 ~ Ub conjugate recognized by a pathogenic bacterial E3 ligaseComplete subunit architecture of the proteasome regulatory particleStructural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitinationDeubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTsRescue of HIV-1 release by targeting widely divergent NEDD4-type ubiquitin ligases and isolated catalytic HECT domains to Gag.Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes.Structural Studies of HHARI/UbcH7∼Ub Reveal Unique E2∼Ub Conformational Restriction by RBR RING1.Structural and functional insights to ubiquitin-like protein conjugation.Stress conditions promote yeast Gap1 permease ubiquitylation and down-regulation via the arrestin-like Bul and Aly proteins.Endocytic adaptor epidermal growth factor receptor substrate 15 (Eps15) is involved in the trafficking of ubiquitinated α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors.Following Ariadne's thread: a new perspective on RBR ubiquitin ligasesAssembly and specific recognition of k29- and k33-linked polyubiquitin.Multiple interactions between the ESCRT machinery and arrestin-related proteins: implications for PPXY-dependent budding.Versatile roles of k63-linked ubiquitin chains in trafficking.Macromolecular juggling by ubiquitylation enzymes.Angiomotin functions in HIV-1 assembly and budding.A single ubiquitin is sufficient for cargo protein entry into MVBs in the absence of ESCRT ubiquitination
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Polyubiquitination by HECT E3s and the determinants of chain type specificity.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 13 April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Polyubiquitination by HECT E3s and the determinants of chain type specificity.
@en
Polyubiquitination by HECT E3s and the determinants of chain type specificity.
@nl
type
label
Polyubiquitination by HECT E3s and the determinants of chain type specificity.
@en
Polyubiquitination by HECT E3s and the determinants of chain type specificity.
@nl
prefLabel
Polyubiquitination by HECT E3s and the determinants of chain type specificity.
@en
Polyubiquitination by HECT E3s and the determinants of chain type specificity.
@nl
P2860
P356
P1476
Polyubiquitination by HECT E3s and the determinants of chain type specificity.
@en
P2093
Hyung Cheol Kim
Jon M Huibregtse
P2860
P304
P356
10.1128/MCB.00240-09
P407
P577
2009-04-13T00:00:00Z