Apolipoprote%C3%AFna_EAPOEApolipoprotein_EApolipoprotein_EApolipoprote%C3%ADna_E%D8%A2%D9%BE%D9%88%D9%84%DB%8C%D9%BE%D9%88%D9%BE%D8%B1%D9%88%D8%AA%D8%A6%DB%8C%D9%86_%D8%A7%DB%8C%DB%8CApolipoproteiini_EApolipoprot%C3%A9ine_EApolipoprote%C3%ADna_EApolipoprotein_EApolipoproteinum_EApolipoprote%C3%AFne_EApolipoproteina_EApolipoprote%C3%ADna_E%D0%90%D0%BF%D0%BE%D0%BB%D0%B8%D0%BF%D0%BE%D0%BF%D1%80%D0%BE%D1%82%D0%B5%D0%B8%D0%BD_EApolipoprotein_E%D0%90%D0%BF%D0%BE%D0%BB%D1%96%D0%BF%D0%BE%D0%BF%D1%80%D0%BE%D1%82%D0%B5%D1%97%D0%BD_EQ424728
about
Ligands of MSR1Ligands of MSR1 [endocytic vesicle lumen]spherical HDL:apoC-II:apoC-III:apoEmature CM:atREsCRCR [early endosome]CR:atREs:HSPG:apoECR:atREs:HSPG:apoE [early endosome]FAM20C substratesFAM20C productschylomicronTG-depleted chylomicronchylomicron remnantchylomicron remnant:apoE complexchylomicron remnant:apoE complex [plasma membrane]chylomicron remnant [plasma membrane]chylomicron remnant:apoE complex [clathrin-coated endocytic vesicle membrane]chylomicron remnant [clathrin-coated endocytic vesicle membrane]chylomicron remnant:apoE complex [endosome membrane]chylomicron remnant [endosome membrane]chylomicron remnant:apoE complex [endosome lumen]chylomicron remnant [endosome lumen]The APOE gene transcription is stimulated by the complex of TFAP2A homodimer and DEKCR:atREs binds apoE and HSPGNREH hydrolyses atREs (HSPG:apoE) to atROL and FAschylomicron remnant + apoE => chylomicron remnant:apoE complexSpherical HDL binds C and E apolipoproteins
P527
P688
Interactions of metals and Apolipoprotein E in Alzheimer's diseaseApolipoprotein specificity for lipid efflux by the human ABCAI transporterQuantitation of apoE domains in Alzheimer disease brain suggests a role for apoE in Abeta aggregationApolipoprotein E modulates Alzheimer's Abeta(1-42)-induced oxidative damage to synaptosomes in an allele-specific mannerRabbit very low density lipoprotein receptor: a low density lipoprotein receptor-like protein with distinct ligand specificityThe C-terminal lipid-binding domain of apolipoprotein E is a highly efficient mediator of ABCA1-dependent cholesterol efflux that promotes the assembly of high-density lipoproteinsApolipoprotein A-V interaction with members of the low density lipoprotein receptor gene familyApolipoprotein E (ApoE) isoform-dependent lipid release from astrocytes prepared from human ApoE3 and ApoE4 knock-in miceFractionation of cholesteryl ester rich intermediate density lipoprotein subpopulations by chondroitin sulphateFamilial apolipoprotein E deficiencyBehavior of human apolipoprotein E in aqueous solutions and at interfacesApolipoprotein E enrichment of immuno-separated chylomicron and chylomicron remnants following saturated fatty acidsApolipoprotein E likely contributes to a maturation step of infectious hepatitis C virus particles and interacts with viral envelope glycoproteinsApolipoprotein A-I activates Cdc42 signaling through the ABCA1 transporterStudies of familial type III hyperlipoproteinemia using as a genetic marker the apoE phenotype E2/2Apoprotein (E--A-II) complex of human plasma lipoproteins. I. Characterization of this mixed disulfide and its identification in a high density lipoprotein subfractionApoprotein (E--A-II) complex of human plasma lipoproteins. II. Receptor binding activity of a high density lipoprotein subfraction modulated by the apo(E--A-II) complexRegulation of ApoE receptor proteolysis by ligand bindingMolecular interactions between apoE and ABCA1: impact on apoE lipidationType III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human Apoe*2ApoE3 binding to tau tandem repeat I is abolished by tau serine262 phosphorylationApoE4 delays dendritic spine formation during neuron development and accelerates loss of mature spines in vitroApolipoprotein E inhibits platelet aggregation through the L-arginine:nitric oxide pathway. Implications for vascular diseaseEvidence for differential effects of apoE3 and apoE4 on HDL metabolismReduction in DHA transport to the brain of mice expressing human APOE4 compared to APOE2Apolipoprotein E inhibits platelet-derived growth factor-induced vascular smooth muscle cell migration and proliferation by suppressing signal transduction and preventing cell entry to G1 phaseDomains of apoE required for binding to apoE receptor 2 and to phospholipids: implications for the functions of apoE in the brainApolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic studyIdentification of disulfide-linked apolipoprotein species in human lipoproteinsApolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microglia in vitroProteomic analysis of human very low-density lipoprotein by two-dimensional gel electrophoresis and MALDI-TOF/TOFMechanisms of inhibition by apolipoprotein C of apolipoprotein E-dependent cellular metabolism of human triglyceride-rich lipoproteins through the low density lipoprotein receptor pathwayThe neurobiology of apolipoproteins and their receptors in the CNS and Alzheimer's diseaseA plasma lipoprotein containing only apolipoprotein E and with gamma mobility on electrophoresis releases cholesterol from cellsApolipoprotein E is the major physiological activator of lecithin-cholesterol acyltransferase (LCAT) on apolipoprotein B lipoproteinsHuman APOE genotype affects intraneuronal Aβ1-42 accumulation in a lentiviral gene transfer modelApolipoprotein E mediates binding of normal very low density lipoprotein to heparin but is not required for high affinity receptor bindingLow density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteinsHuman apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3 and E4 isoformsThe importance of Wnt signalling for neurodegeneration in Parkinson's disease
P921
Q50177694-B4F0E829-4EA2-4D45-BA94-A9642A5D49FCQ50181452-DE90DCC2-BD56-47CC-9F4F-433175E955FAQ50266467-C37D57C0-5085-4E1A-B7FA-3F1C3B7503D0Q50266470-9FE9FBC9-E490-45F9-8422-3E764B209D21Q50266475-EA99BF27-93D3-46A3-A4EF-88271FE04011Q50266487-CB66B673-7220-403D-89E3-D32B4858FB80Q50266494-1FFF98A1-FE16-4167-8463-6329833A9275Q50266496-BCAC5D6E-3550-4E7C-AE17-786F1CB2CCEFQ50269397-370BD940-599B-446F-ABD7-3EEFFD5D4453Q50269401-A065DEAB-2535-4998-A836-E59CD61885D0Q50274715-135E7DC3-2DB6-4C72-AFF6-7C5C8E0478C7Q50274739-F79F7AF6-A5B7-4A99-9466-6B8050D49973Q50274741-38D019AD-EF2F-405B-A17D-D19AD8B9C52BQ50274742-B98ACD9E-1906-4024-BDA8-B9089D7C9D46Q50274759-20258448-7052-4A5D-8DB1-21B6ADA33348Q50274760-38537659-DCD6-4934-9421-A2A60C473432Q50274763-92493F74-A555-4BBB-96EB-FE999ECD2E70Q50274764-09FC19F8-F754-4262-876B-443EBC2F1837Q50274768-56F228EB-FACF-444F-BFC6-6D96DC73DDD6Q50274769-C67D29B8-D6E5-46DA-A4F9-F7831AEAEAD7Q50274771-367A2AB8-7C7C-4C21-90BB-1A9E46CED7B0Q50274772-6510B392-74F4-40FE-81FE-776B9D8AA6BDQ50290460-99994D83-BC56-4A7E-8F33-71496F710FEBQ50294890-862CDAE3-148F-48F1-B12C-4185934C8B96Q50294893-20C208A1-8BC6-4D55-BC4F-A173D0B55918Q50299759-AD958BA4-D3DD-4E76-B389-0AA323823385Q50299765-FC9C5F77-2A6C-4264-AAB9-5CC241E33897
P527
Q21131068-4dc2dee1-45ad-3611-fbba-aa854626f2fbQ24290771-BD4371AF-5E16-48DF-84FC-05D5099FD9D9Q24291128-016257B1-E04B-4EC8-9701-36A1ED8AB357Q24292032-AA6948CB-CC81-421C-A824-422C9CC6677DQ24293268-908ED266-A44B-42E9-A15E-F98DE50B23A2Q24297456-833B4DF4-493B-45EE-BD37-0E22F4BB0B82Q24298481-7700E674-229E-4B7C-9BC9-EB6958E16ABEQ24298652-1E3D6C30-280E-48F4-9ABE-E86B0286B4C3Q24299052-3843F24B-67F0-415D-8445-0B415F92E421Q24299817-4B3CE9E1-704F-442F-B5AA-00B54B2356AEQ24300390-1554C41E-1CDA-41C7-9875-E2715DDCA560Q24300786-E2F4BD3D-9C47-453B-BA8A-31E1033EC411Q24301976-7051D280-10D6-46CA-A971-524CE33E2272Q24302387-838B9CD3-CC17-47C3-8653-5AAC46DEF0D0Q24302533-DB11F36A-DF17-44FA-9524-84BE7D4A27A7Q24304498-AF878910-844F-473F-BEA5-7D03DCDA95BEQ24304510-A99D377F-657C-44FE-BF5F-CC8BD3E4E5D1Q24305144-289E31D8-B8ED-4DF4-A9B0-BBC0CD59D1ACQ24306797-4034BD3D-0FFD-4080-AA3C-9CA0A334374BQ24310889-12A5C05A-D1C1-4A46-B133-3FFB6D3ECEC7Q24311818-D0C89A87-D08B-443E-95D3-3EE683FC17CEQ24312075-7B3AB14C-A977-4C9C-9C75-B9832822E5B9Q24312335-52A40EA5-F455-4BC8-AB8F-B6C924574320Q24313446-A174E97E-64DD-4F17-A036-2CF6D9666131Q24314295-674E97A8-A5E8-4D32-8BC3-E7B424067353Q24318760-A8A15D60-3B95-4B67-BD73-D74EE50AA704Q24319092-9A26184B-D341-4EB5-AADB-B394A9ADFD6BQ24319783-1854115F-D050-40F9-8299-FE2CBA62D0DCQ24320060-2BB44082-9276-4A57-994D-13CD83A7BB5AQ24321663-D3890A7B-1AC6-442A-9502-1442C8BEB8AEQ24323213-5B92DA01-F13C-4F7F-91BA-242D95509C60Q24323234-AC761B20-5561-47C4-A47C-85D9C6379D33Q24324223-D28CE4AE-3893-4677-9A83-595F15F54E31Q24336518-1C01B0DA-8DEC-4B30-A800-8A2984821210Q24338313-4124B828-AFCE-4188-8748-5FD1928E3EA1Q24338827-87321DC6-12C4-4D85-8514-DBE63751B04AQ24339545-2E64C76B-8D06-4AF3-BEF1-76511C23C9C5Q24609758-D77DD49E-3EF1-4391-8CED-D6FAE70ACC37Q27730887-66FA5F87-7936-4513-B188-C19264249E09Q28115237-040BB6A9-0E49-43BF-9704-21AF7A929A20
P921
description
Protein
@de
mammalian protein found in Homo sapiens
@en
protein hos Homo sapiens
@da
protein
@id
protein
@sv
proteinë
@sq
proteïne in Apolipoprotein E
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
APOE
@cy
Apolipoproteiini E
@fi
Apolipoprotein E
@da
Apolipoprotein E
@de
Apolipoprotein E
@en
Apolipoprotein E
@hr
Apolipoprotein E
@nl
Apolipoprotein E
@tr
Apolipoproteina E
@pl
Apolipoproteinum E
@la
type
label
APOE
@cy
Apolipoproteiini E
@fi
Apolipoprotein E
@da
Apolipoprotein E
@de
Apolipoprotein E
@en
Apolipoprotein E
@hr
Apolipoprotein E
@nl
Apolipoprotein E
@tr
Apolipoproteina E
@pl
Apolipoproteinum E
@la
altLabel
AD2
@en
APOE
@en
APOE
@ru
Apo E
@es
ApoE
@ca
ApoE
@de
ApoE
@fi
ApoE
@tr
ApoE4
@fi
Apoe
@es
prefLabel
APOE
@cy
Apolipoproteiini E
@fi
Apolipoprotein E
@da
Apolipoprotein E
@de
Apolipoprotein E
@en
Apolipoprotein E
@hr
Apolipoprotein E
@nl
Apolipoprotein E
@tr
Apolipoproteina E
@pl
Apolipoproteinum E
@la
P486
P637
P638
P680
P681
P682
P705
P352
P6366
P646
P2888
P31
P3417
Apolipoprotein-E
P352
P486
P6366
P637
NP_001289617
NP_001289618
NP_001289619
NP_001289620
P638
P646
P680
P681
P682
P702
P703
P705
ENSP00000252486
ENSP00000410423
ENSP00000413135
ENSP00000413653