Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility.
about
An X-linked gene encodes a major human sperm fibrous sheath protein, hAKAP82. Genomic organization, protein kinase A-RII binding, and distribution of the precursor in the sperm tailA novel isoform of human cyclic 3',5'-adenosine monophosphate-dependent protein kinase, c alpha-s, localizes to sperm midpieceIsolation and characterization of two novel phosphodiesterase PDE11A variants showing unique structure and tissue-specific expressionIdentification of sperm-specific proteins that interact with A-kinase anchoring proteins in a manner similar to the type II regulatory subunit of PKARadixin assembles cAMP effectors Epac and PKA into a functional cAMP compartment: role in cAMP-dependent cell proliferationAn anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamicsC2orf62 and TTC17 are involved in actin organization and ciliogenesis in zebrafish and humanA novel mechanism of PKA anchoring revealed by solution structures of anchoring complexesHuman spermatozoa contain multiple targets for protein S-nitrosylation: an alternative mechanism of the modulation of sperm function by nitric oxide?Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoringMolecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling UnitsTherapeutic strategies for anchored kinases and phosphatases: exploiting short linear motifs and intrinsic disorderChanges in Carboxy Methylation and Tyrosine Phosphorylation of Protein Phosphatase PP2A Are Associated with Epididymal Sperm Maturation and MotilityAssociation of protein kinase A with AKAP150 facilitates pepsinogen secretion from gastric chief cellsNetworking with AKAPs: context-dependent regulation of anchored enzymesEvidence for involvement of A-kinase anchoring protein in activation of rat arterial K(ATP) channels by protein kinase AAMP-activated kinase AMPK is expressed in boar spermatozoa and regulates motilityLoss of ASP but not ROPN1 reduces mammalian ciliary motilityA protein kinase encoded by the t complex responder gene causes non-mendelian inheritanceDissociation between AKAP3 and PKARII promotes AKAP3 degradation in sperm capacitationAKAP79-mediated targeting of the cyclic AMP-dependent protein kinase to the beta1-adrenergic receptor promotes recycling and functional resensitization of the receptorExpression of a kinase anchor protein 121 is regulated by hormones in thyroid and testicular germ cellsTargeting of protein kinase A by muscle A kinase-anchoring protein (mAKAP) regulates phosphorylation and function of the skeletal muscle ryanodine receptorLoss of R2D2 proteins ROPN1 and ROPN1L causes defects in murine sperm motility, phosphorylation, and fibrous sheath integrityBinding and phosphorylation of a novel male germ cell-specific cGMP-dependent protein kinase-anchoring protein by cGMP-dependent protein kinase IalphaFSP95, a testis-specific 95-kilodalton fibrous sheath antigen that undergoes tyrosine phosphorylation in capacitated human spermatozoa.The flagellar motility of Chlamydomonas pf25 mutant lacking an AKAP-binding protein is overtly sensitive to medium conditions.Peptide modulators of protein-protein interactions in intracellular signaling.Design of proteolytically stable RI-anchoring disruptor peptidomimetics for in vivo studies of anchored type I protein kinase A-mediated signalling.Roles of the oviduct in mammalian fertilization.Validation of a laboratory-developed test of human sperm capacitationIon channels, phosphorylation and mammalian sperm capacitation.Reproductive function in protein kinase inhibitor-deficient mice.Compartmentalized PKA signaling events are required for synaptic tagging and capture during hippocampal late-phase long-term potentiationGenetic disruption of protein kinase A anchoring reveals a role for compartmentalized kinase signaling in theta-burst long-term potentiation and spatial memory.Central role of soluble adenylyl cyclase and cAMP in sperm physiology.Designing isoform-specific peptide disruptors of protein kinase A localization.Contemporary evidence on the physiological role of reactive oxygen species in human sperm function.Selective disruption of the AKAP signaling complexesTeasing out the role of aromatase in the healthy and diseased testis.
P2860
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P2860
Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility.
@en
Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility.
@nl
type
label
Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility.
@en
Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility.
@nl
prefLabel
Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility.
@en
Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility.
@nl
P2093
P2860
P356
P1476
Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility.
@en
P2093
Vijayaraghavan S
P2860
P304
P356
10.1074/JBC.272.8.4747
P407
P577
1997-02-01T00:00:00Z