Type 1 sodium-dependent phosphate transporter (SLC17A1 Protein) is a Cl(-)-dependent urate exporter.
about
The genetics of hyperuricaemia and goutUrate Handling in the Human BodyRenal transport of uric acid: evolving concepts and uncertaintiesSLC17: a functionally diverse family of organic anion transportersExtra-renal elimination of uric acid via intestinal efflux transporter BCRP/ABCG2Fructose Intake, Serum Uric Acid, and Cardiometabolic Disorders: A Critical Review.The Concise Guide to PHARMACOLOGY 2013/14: transporters.Gout, genetics and ABC transporters.Polymorphisms in GCKR, SLC17A1 and SLC22A12 were associated with phenotype gout in Han Chinese males: a case-control study.Genome-wide association study identifies ABCG2 (BCRP) as an allopurinol transporter and a determinant of drug response.Successful prediction of substrate-binding pocket in SLC17 transporter sialin.The renal urate transporter SLC17A1 locus: confirmation of association with gout.The pharmacokinetics of oxypurinol in people with gout.Uricosuric targets of tranilast.Apical voltage-driven urate efflux transporter NPT4 in renal proximal tubule.Renal transport of organic anions and cations.Renal handling of phosphate and sulfate.Regulation of renal phosphate handling: inter-organ communication in health and disease.Time to target uric acid to retard CKD progression.Vesicular nucleotide transporter (VNUT): appearance of an actress on the stage of purinergic signaling.Divalent cation transport by vesicular nucleotide transporter.Mechanism of high affinity inhibition of the human urate transporter URAT1Metabolic control of vesicular glutamate transport and release.Expression of a human NPT1/SLC17A1 missense variant which increases urate export.NPT1/SLC17A1 is a renal urate exporter in humans and its common gain-of-function variant decreases the risk of renal underexcretion gout.Population-specific effects of SLC17A1 genotype on serum urate concentrations and renal excretion of uric acid during a fructose load.Wide expression of type I Na+-phosphate cotransporter 3 (NPT3/SLC17A2), a membrane potential-driven organic anion transporter.A Na+-phosphate cotransporter homologue (SLC17A4 protein) is an intestinal organic anion exporter.Genetic variants in two pathways influence serum urate levels and gout risk: a systematic pathway analysis.Probable Potential Role of Urate Transporter Genes in the Development of Metabolic Disorders.Physiology of Hyperuricemia and Urate-Lowering Treatments.Multiple Membrane Transporters and Some Immune Regulatory Genes are Major Genetic Factors to Gout
P2860
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P2860
Type 1 sodium-dependent phosphate transporter (SLC17A1 Protein) is a Cl(-)-dependent urate exporter.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Type 1 sodium-dependent phosph ...... l(-)-dependent urate exporter.
@en
Type 1 sodium-dependent phosphate transporter
@nl
type
label
Type 1 sodium-dependent phosph ...... l(-)-dependent urate exporter.
@en
Type 1 sodium-dependent phosphate transporter
@nl
prefLabel
Type 1 sodium-dependent phosph ...... l(-)-dependent urate exporter.
@en
Type 1 sodium-dependent phosphate transporter
@nl
P2093
P2860
P356
P1476
Type 1 sodium-dependent phosph ...... l(-)-dependent urate exporter.
@en
P2093
Hiroshi Omote
Masafumi Iharada
Miki Hiasa
Takaaki Miyaji
Takahiro Fujimoto
Yoshinori Moriyama
P2860
P304
26107-26113
P356
10.1074/JBC.M110.122721
P407
P577
2010-06-21T00:00:00Z