Total synthesis and pharmacological characterization of solomonsterol A, a potent marine pregnane-X-receptor agonist endowed with anti-inflammatory activity.

Total synthesis and pharmacological characterization of solomonsterol A, a potent marine pregnane-X-receptor agonist endowed with anti-inflammatory activity.

Item
http://www.wikidata.org/entity/Q42733749
Pregnane X receptor as a target for treatment of inflammatory bowel disordersModulation of xenobiotic receptors by steroidsAlleviation of gut inflammation by Cdx2/Pxr pathway in a mouse model of chemical colitisMarine and semi-synthetic hydroxysteroids as new scaffolds for pregnane X receptor modulationPerthamide C inhibits eNOS and iNOS expression and has immunomodulating activity in vivo.Coral-derived compound WA-25 inhibits angiogenesis by attenuating the VEGF/VEGFR2 signaling pathwaySmall-molecule modulators of PXR and CAR.Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists.Solomonsterol A, a marine pregnane-X-receptor agonist, attenuates inflammation and immune dysfunction in a mouse model of arthritis.Targeting nuclear receptors with marine natural products.Marine natural products with anti-inflammatory activity.Phallusiasterols A and B: two new sulfated sterols from the Mediterranean tunicate Phallusia fumigata and their effects as modulators of the PXR receptor.Oxygenated polyketides from Plakinastrella mamillaris as a new chemotype of PXR agonists.Chalinulasterol, a chlorinated steroid disulfate from the Caribbean sponge Chalinula molitba. Evaluation of its role as PXR receptor modulator.Modification in the side chain of solomonsterol A: discovery of cholestan disulfate as a potent pregnane-X-receptor agonist.Preliminary structure-activity relationship on theonellasterol, a new chemotype of FXR antagonist, from the marine sponge Theonella swinhoei.
P2860

Total synthesis and pharmacological characterization of solomonsterol A, a potent marine pregnane-X-receptor agonist endowed with anti-inflammatory activity.

Item
http://www.wikidata.org/entity/Q42733749
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Total synthesis and pharmacolo ...... th anti-inflammatory activity.
@en
Total synthesis and pharmacolo ...... th anti-inflammatory activity.
@nl
type
label
Total synthesis and pharmacolo ...... th anti-inflammatory activity.
@en
Total synthesis and pharmacolo ...... th anti-inflammatory activity.
@nl
prefLabel
Total synthesis and pharmacolo ...... th anti-inflammatory activity.
@en
Total synthesis and pharmacolo ...... th anti-inflammatory activity.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P356
P1433
P1476
Total synthesis and pharmacolo ...... th anti-inflammatory activity.
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921