about
Trim24 targets endogenous p53 for degradationTRIM24 is a p53-induced E3-ubiquitin ligase that undergoes ATM-mediated phosphorylation and autodegradation during DNA damagep53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells.Unmet expectations: miR-34 plays no role in p53-mediated tumor suppression in vivo.Making sense of ubiquitin ligases that regulate p53.Analysis of epigenetic alterations to chromatin during development.Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cellsBromodomain Histone Readers and Cancer.An auto-regulatory loop between stress sensors INrf2 and Nrf2 controls their cellular abundance.GSK-3beta acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2.LncPRESS1 Is a p53-Regulated LncRNA that Safeguards Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56.TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.Outside the p53 RING: Transcription Regulation by Chromatin-Bound MDM2.Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-kappaB, IkappaBalpha kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis.p53: emerging roles in stem cells, development and beyondAberrant expression of embryonic mesendoderm factor MESP1 promotes tumorigenesisVerteporfin inhibits PD-L1 through autophagy and the STAT1-IRF1-TRIM28 signaling axis, exerting antitumor efficacy
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Abhinav K Jain
@ast
Abhinav K Jain
@en
Abhinav K Jain
@es
Abhinav K Jain
@nl
type
label
Abhinav K Jain
@ast
Abhinav K Jain
@en
Abhinav K Jain
@es
Abhinav K Jain
@nl
prefLabel
Abhinav K Jain
@ast
Abhinav K Jain
@en
Abhinav K Jain
@es
Abhinav K Jain
@nl
P106
P21
P31
P496
0000-0003-3268-514X
P569
2000-01-01T00:00:00Z