Alternative splicing of the actin binding domain of human cortactin affects cell migration. - Test2 - elhamkhani - TriplyDB

Alternative splicing of the actin binding domain of human cortactin affects cell migration.

Alternative splicing of the actin binding domain of human cortactin affects cell migration.

http://www.wikidata.org/entity/Q42797503

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Comparative genome analysis of cortactin and HS1: the significance of the F-actin binding repeat domain Direct dynamin-actin interactions regulate the actin cytoskeleton.PTP1B regulates cortactin tyrosine phosphorylation by targeting Tyr446 Cortactin signalling and dynamic actin networks BPGAP1 interacts with cortactin and facilitates its translocation to cell periphery for enhanced cell migration Cortactin branches out: roles in regulating protrusive actin dynamics Cortactin overexpression results in sustained epidermal growth factor receptor signaling by preventing ligand-induced receptor degradation in human carcinoma cells.Tuning cell migration: contractility as an integrator of intracellular signals from multiple cues PI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin-actin interactions.Cortactin phosphorylated by ERK1/2 localizes to sites of dynamic actin regulation and is required for carcinoma lamellipodia persistence Phosphorylation of the alternative mRNA splicing factor 45 (SPF45) by Clk1 regulates its splice site utilization, cell migration and invasion.Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases.Transgenic mice with mammary gland targeted expression of human cortactin do not develop (pre-malignant) breast tumors: studies in MMTV-cortactin and MMTV-cortactin/-cyclin D1 bitransgenic mice Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array.Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemia High expression of PTBP1 promote invasion of colorectal cancer by alternative splicing of cortactin.Comprehensive exon array data processing method for quantitative analysis of alternative spliced variants.Cortactin: a multifunctional regulator of cellular invasiveness Differential protein expression profiles in estrogen receptor-positive and -negative breast cancer tissues using label-free quantitative proteomics.Abl2/Abl-related gene stabilizes actin filaments, stimulates actin branching by actin-related protein 2/3 complex, and promotes actin filament severing by cofilin.Cortactin colocalizes with filopodial actin and accumulates at IgCAM adhesion sites in Aplysia growth cones.Cortactin expression predicts poor survival in laryngeal carcinoma Alternative Splicing in Adhesion- and Motility-Related Genes in Breast Cancer Decreased expression of cortactin in the schizophrenia brain Oncogenic alternative splicing switches: role in cancer progression and prospects for therapy.Dynamin rings: not just for fission.Cortactin in cell migration and cancer at a glance Cortactin adopts a globular conformation and bundles actin into sheets.Cortactin function in invadopodia.Overexpression of cortactin in head and neck squamous cell carcinomas can be uncoupled from augmented EGF receptor expression.

P2860

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P2860

Alternative splicing of the actin binding domain of human cortactin affects cell migration.

http://www.wikidata.org/entity/Q42797503

description

2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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2003年论文

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2003年论文

@zh-cn

name

Alternative splicing of the ac ...... tactin affects cell migration.

@en

Alternative splicing of the ac ...... tactin affects cell migration.

@nl

type

label

Alternative splicing of the ac ...... tactin affects cell migration.

@en

Alternative splicing of the ac ...... tactin affects cell migration.

@nl

prefLabel

Alternative splicing of the ac ...... tactin affects cell migration.

@en

Alternative splicing of the ac ...... tactin affects cell migration.

@nl

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P1433

Journal of Biological Chemistry

P1476

Alternative splicing of the ac ...... tactin affects cell migration.

@en

P2093

Agnes G S H van Rossum

http://www.w3.org/2001/XMLSchema#string

Ed Schuuring

http://www.w3.org/2001/XMLSchema#string

Ellen Schuuring-Scholtes

http://www.w3.org/2001/XMLSchema#string

Jos H de Graaf

http://www.w3.org/2001/XMLSchema#string

Philip M Kluin

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Wouter H Moolenaar

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Xi Zhan

http://www.w3.org/2001/XMLSchema#string

Ying-Xin Fan

http://www.w3.org/2001/XMLSchema#string

P2860

Activation of Arp2/3 complex-mediated actin polymerization by cortactin

Sequential interaction of actin-related proteins 2 and 3 (Arp2/3) complex with neural Wiscott-Aldrich syndrome protein (N-WASP) and cortactin during branched actin filament network formation

The redistribution of cortactin into cell-matrix contact sites in human carcinoma cells with 11q13 amplification is associated with both overexpression and post-translational modification

The product of the EMS1 gene, amplified and overexpressed in human carcinomas, is homologous to a v-src substrate and is located in cell-substratum contact sites

Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex.

Cortactin: coupling membrane dynamics to cortical actin assembly

Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation

The role of tyrosine phosphorylation of cortactin in the locomotion of endothelial cells

Cortactin associates with the cell-cell junction protein ZO-1 in both Drosophila and mouse

Isolation and characterization of cortactin isoforms and a novel cortactin-binding protein, CBP90

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45672-45679

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scholarly article

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10.1074/JBC.M306688200

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P433

46

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P478

278

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2003-09-02T00:00:00Z

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12952985

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