Alternative splicing of the actin binding domain of human cortactin affects cell migration.
about
Comparative genome analysis of cortactin and HS1: the significance of the F-actin binding repeat domainDirect dynamin-actin interactions regulate the actin cytoskeleton.PTP1B regulates cortactin tyrosine phosphorylation by targeting Tyr446Cortactin signalling and dynamic actin networksBPGAP1 interacts with cortactin and facilitates its translocation to cell periphery for enhanced cell migrationCortactin branches out: roles in regulating protrusive actin dynamicsCortactin overexpression results in sustained epidermal growth factor receptor signaling by preventing ligand-induced receptor degradation in human carcinoma cells.Tuning cell migration: contractility as an integrator of intracellular signals from multiple cuesPI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin-actin interactions.Cortactin phosphorylated by ERK1/2 localizes to sites of dynamic actin regulation and is required for carcinoma lamellipodia persistencePhosphorylation of the alternative mRNA splicing factor 45 (SPF45) by Clk1 regulates its splice site utilization, cell migration and invasion.Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases.Transgenic mice with mammary gland targeted expression of human cortactin do not develop (pre-malignant) breast tumors: studies in MMTV-cortactin and MMTV-cortactin/-cyclin D1 bitransgenic miceAlternative splicing and differential gene expression in colon cancer detected by a whole genome exon array.Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemiaHigh expression of PTBP1 promote invasion of colorectal cancer by alternative splicing of cortactin.Comprehensive exon array data processing method for quantitative analysis of alternative spliced variants.Cortactin: a multifunctional regulator of cellular invasivenessDifferential protein expression profiles in estrogen receptor-positive and -negative breast cancer tissues using label-free quantitative proteomics.Abl2/Abl-related gene stabilizes actin filaments, stimulates actin branching by actin-related protein 2/3 complex, and promotes actin filament severing by cofilin.Cortactin colocalizes with filopodial actin and accumulates at IgCAM adhesion sites in Aplysia growth cones.Cortactin expression predicts poor survival in laryngeal carcinomaAlternative Splicing in Adhesion- and Motility-Related Genes in Breast CancerDecreased expression of cortactin in the schizophrenia brainOncogenic alternative splicing switches: role in cancer progression and prospects for therapy.Dynamin rings: not just for fission.Cortactin in cell migration and cancer at a glanceCortactin adopts a globular conformation and bundles actin into sheets.Cortactin function in invadopodia.Overexpression of cortactin in head and neck squamous cell carcinomas can be uncoupled from augmented EGF receptor expression.
P2860
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P2860
Alternative splicing of the actin binding domain of human cortactin affects cell migration.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Alternative splicing of the ac ...... tactin affects cell migration.
@en
Alternative splicing of the ac ...... tactin affects cell migration.
@nl
type
label
Alternative splicing of the ac ...... tactin affects cell migration.
@en
Alternative splicing of the ac ...... tactin affects cell migration.
@nl
prefLabel
Alternative splicing of the ac ...... tactin affects cell migration.
@en
Alternative splicing of the ac ...... tactin affects cell migration.
@nl
P2093
P2860
P356
P1476
Alternative splicing of the ac ...... tactin affects cell migration.
@en
P2093
Agnes G S H van Rossum
Ed Schuuring
Ellen Schuuring-Scholtes
Jos H de Graaf
Philip M Kluin
Wouter H Moolenaar
Ying-Xin Fan
P2860
P304
45672-45679
P356
10.1074/JBC.M306688200
P407
P577
2003-09-02T00:00:00Z