Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels.
about
How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?The replication domain model: regulating replicon firing in the context of large-scale chromosome architectureG2 phase chromatin lacks determinants of replication timing.Control of DNA replication by cyclin-dependent kinases in developmentChromatin structure and replication origins: determinants of chromosome replication and nuclear organizationChromatin replication and epigenome maintenance.Cell fate transitions and the replication timing decision point.DNA replication timingCyclin-dependent kinase regulates the length of S phase through TICRR/TRESLIN phosphorylation.Dynamics of DNA replication during premeiosis and early meiosis in wheatFrom egg to gastrula: how the cell cycle is remodeled during the Drosophila mid-blastula transition.Embryonic onset of late replication requires Cdc25 down-regulation.Overexpression of hepatocyte nuclear factor-4α initiates cell cycle entry, but is not sufficient to promote β-cell expansion in human isletsReplicating Large Genomes: Divide and Conquer.Uncovering the role of APC-Cdh1 in generating the dynamics of S-phase onsetHow dormant origins promote complete genome replication.Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication.Replication timing and its emergence from stochastic processesDormant origins, the licensing checkpoint, and the response to replicative stressesRegulation of the g1/s transition in hepatocytes: involvement of the cyclin-dependent kinase cdk1 in the DNA replication.The contribution of dormant origins to genome stability: from cell biology to human genetics.Possible role of H1 histone in replication timing.The essential kinase ATR: ensuring faithful duplication of a challenging genome.Mutant p53 establishes targetable tumor dependency by promoting unscheduled replication.Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress.Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories.Checkpoint recovery after DNA damage: a rolling stop for CDKs.Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1.Clusters, factories and domains: The complex structure of S-phase comes into focus.Stochastic association of neighboring replicons creates replication factories in budding yeast.Dual phosphorylation of cdk1 coordinates cell proliferation with key developmental processes in Drosophila.The Ph1 locus suppresses Cdk2-type activity during premeiosis and meiosis in wheat.CDK activity provides temporal and quantitative cues for organizing genome duplication.Mechanisms of Oncogene-Induced Replication Stress: Jigsaw Falling into Place.Cdks set the replication schedule.
P2860
Q24634200-3A990310-7C7C-4FDD-A602-9A8725AA9F5EQ26825520-6B62D454-E2AE-4477-A3BD-0DA0DC5339BBQ33916079-6AAEFC49-CE56-4A21-AA8E-7CCACEB25D6DQ33918547-2BCC3F3C-0531-4CA0-A9A5-E7EBE3BBECABQ34254857-32AEDB6A-D503-4299-BA3D-D7EA3B3264F0Q34256428-22F63CCD-FB1C-4485-9989-83A46DBACD94Q34368559-160622EC-22CC-4D68-838D-346AB8CE60D7Q34654036-9B20DFB8-4D1A-4AE0-ACC6-691AE3AE49CEQ35173302-A41728ED-7ED0-4407-AAE5-B867A027BAFDQ35294074-3728421D-B571-4424-A0F4-D3A95551A89BQ35794854-0F219A66-36BC-4C58-A242-A240744D2A82Q35882159-0BCE0A62-EF39-45B3-9C0A-65EC5B4CEDCFQ36210995-406FD8AF-4572-4A01-8581-39A658043F99Q36969038-7B529913-3A6E-4823-99F3-3479999FF8FEQ37582528-05037389-445D-4B61-8764-B3A7CC2AD44AQ37884997-38DC026A-5477-43C7-9296-769785770A6CQ37936675-2CB608BC-08C2-430C-BDA4-7612EEFDBA5FQ38004190-C1DD813C-71F1-4989-9456-A3305CBF4377Q38035836-5BF4638E-4A95-40D2-A97F-B88E157724A6Q38054735-5E47BE60-A42C-4117-A0A0-1010D864CF79Q38207300-9B052491-1581-47FA-8A25-1B63581574B7Q38286216-C23A95AB-6217-4EEE-97CA-95466344DDA8Q38622938-9AB1FA28-15DD-44BB-9C03-8045FAC7F33CQ38844605-5354EFE7-8A79-4B9C-A11E-69D4B3CB2FE0Q39285948-501CAC5C-1E17-4048-AC20-CD48E6A6A160Q39617777-8B3A07E7-0ED6-4903-8033-DA2938CD5C60Q41462808-0C738A20-57B7-457E-AE3E-5DF0CB966E80Q41809632-2036ED45-93A3-41EC-9F26-3D7C32DBA2F9Q41813815-6194C03B-CAF3-421D-BD76-658C602621FFQ41997371-D76B0092-03DE-49ED-958A-8CC76F42AE67Q42777134-88CDA80C-7681-4082-871E-8D772B5D6B72Q44293639-1D8D0389-F8C0-4A00-8905-F1A1969B4275Q50335432-98F279EF-CD3C-4B2D-9D5A-A78409802538Q52321974-09F184B8-B4E4-4FA3-A550-783EA39F7CDFQ55429563-B020F30F-A180-41B1-A881-4BCD1183EB52
P2860
Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Replication factory activation ...... gram by modulating Cdk levels.
@en
Replication factory activation ...... gram by modulating Cdk levels.
@nl
type
label
Replication factory activation ...... gram by modulating Cdk levels.
@en
Replication factory activation ...... gram by modulating Cdk levels.
@nl
prefLabel
Replication factory activation ...... gram by modulating Cdk levels.
@en
Replication factory activation ...... gram by modulating Cdk levels.
@nl
P2860
P356
P1476
Replication factory activation ...... ogram by modulating Cdk levels
@en
P2093
Peter J Gillespie
P2860
P304
P356
10.1083/JCB.200911037
P407
P577
2010-01-18T00:00:00Z