Preventing re-replication of chromosomal DNA. - Test2 - elhamkhani - TriplyDB

Preventing re-replication of chromosomal DNA.

Preventing re-replication of chromosomal DNA.

http://www.wikidata.org/entity/Q24653685

about

Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer An overview of Cdk1-controlled targets and processes ORC binding to TRF2 stimulates OriP replication Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progression Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.Cell cycle-dependent formation of Cdc45-Claspin complexes in human cells is compromized by UV-mediated DNA damage Identification and functional analysis of a novel cyclin e/cdk2 substrate ankrd17 RNA-dependent recruitment of the origin recognition complex The chromosome cycle: coordinating replication and segregation. Second in the cycles review series.Regulation of replication licensing by acetyltransferase Hbo1.Distinct roles for Sld3 and GINS during establishment and progression of eukaryotic DNA replication forks Genome-wide mapping of DNA synthesis in Saccharomyces cerevisiae reveals that mechanisms preventing reinitiation of DNA replication are not redundant.Visual activity regulates neural progenitor cells in developing xenopus CNS through musashi1 Prevention of DNA re-replication in eukaryotic cells Replication licensing and cancer--a fatal entanglement?Domain architecture and biochemical characterization of vertebrate Mcm10 Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing Selective killing of cancer cells by suppression of geminin activity Ab ovo or de novo? Mechanisms of centriole duplication The evolution of meiosis from mitosis The anaphase-promoting complex/cyclosome (APC/C) is required for rereplication control in endoreplication cycles Mechanisms to control rereplication and implications for cancer.DNA damage induces Cdt1 proteolysis in fission yeast through a pathway dependent on Cdt2 and Ddb1 Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle The Non-Canonical Role of Aurora-A in DNA Replication Network calisthenics: control of E2F dynamics in cell cycle entry Polo-like kinase 1, on the rise from cell cycle regulation to prostate cancer development Regulation of Unperturbed DNA Replication by Ubiquitylation 3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression.S phase progression in human cells is dictated by the genetic continuity of DNA foci Structure of the human GINS complex and its assembly and functional interface in replication initiation Crystal structure of the GINS complex and functional insights into its role in DNA replication Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing Structure and Mutagenesis Studies of the C-terminal Region of Licensing Factor Cdt1 Enable the Identification of Key Residues for Binding to Replicative Helicase Mcm Proteins The Geminin and Idas Coiled Coils Preferentially Form a Heterodimer That Inhibits Geminin Function in DNA Replication Licensing The Hect domain E3 ligase Tom1 and the F-box protein Dia2 control Cdc6 degradation in G1 phase Differential requirement of DNA replication factors for subtelomeric ARS consensus sequence protosilencers in Saccharomyces cerevisiae.A CDK-catalysed regulatory phosphorylation for formation of the DNA replication complex Sld2-Dpb11 A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome.

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Preventing re-replication of chromosomal DNA.

http://www.wikidata.org/entity/Q24653685

description

2005 nî lūn-bûn

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2005 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2005 թվականի հունիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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Preventing re-replication of chromosomal DNA

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Preventing re-replication of chromosomal DNA.

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Preventing re-replication of chromosomal DNA.

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Preventing re-replication of chromosomal DNA

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Preventing re-replication of chromosomal DNA.

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Preventing re-replication of chromosomal DNA.

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prefLabel

Preventing re-replication of chromosomal DNA

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Preventing re-replication of chromosomal DNA.

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Preventing re-replication of chromosomal DNA.

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Nature Reviews Molecular Cell Biology

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Preventing re-replication of chromosomal DNA

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J Julian Blow

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P2860

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication

The regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cells

Geminin, an inhibitor of DNA replication, is degraded during mitosis

Direct interaction of geminin and Six3 in eye development

Human CDC6/Cdc18 associates with Orc1 and cyclin-cdk and is selectively eliminated from the nucleus at the onset of S phase

Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding

A DNA helicase activity is associated with an MCM4, -6, and -7 protein complex

Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization

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476-486

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scholarly article

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945793

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10.1038/NRM1663

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1012862888

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