Ligand efficiency indices for an effective mapping of chemico-biological space: the concept of an atlas-like representation.
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Hit identification and optimization in virtual screening: practical recommendations based on a critical literature analysisChemical, target, and bioactive properties of allosteric modulationMycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validationNovel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screenRetrospective Mapping of SAR Data for TTR Protein in Chemico-Biological Space Using Ligand Efficiency Indices as a Guide to Drug Discovery Strategies.Recent trends and observations in the design of high-quality screening collections.Collation and data-mining of literature bioactivity data for drug discovery.AtlasCBS: a web server to map and explore chemico-biological space.Synergistic inhibitor binding to the papain-like protease of human SARS coronavirus: mechanistic and inhibitor design implications.Biomolecular chemistry of isopropyl fibratesDisease-Specific Differentiation Between Drugs and Non-Drugs Using Principal Component Analysis of Their Molecular Descriptor Space.Biophysical limits of protein-ligand binding.Identification of potential inhibitors based on compound proposal contest: Tyrosine-protein kinase Yes as a target.Ligand-receptor interaction platforms and their applications for drug discovery.Combining label-free cell phenotypic profiling with computational approaches for novel drug discovery.Ligand Efficiency Indices (LEIs): More than a Simple Efficiency Yardstick.Thioflavin-based molecular probes for application in Alzheimer's disease: from in silico to in vitro models.Alternative variables in drug discovery: promises and challenges.Mappability of drug-like space: towards a polypharmacologically competent map of drug-relevant compounds.Understanding the foundations of the structural similarities between marketed drugs and endogenous human metabolitesTarget Identification of Mycobacterium tuberculosis Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach.In silico ligand-based modeling of hBACE-1 inhibitors.Ligand efficiency metrics in drug discovery: the pros and cons from a practical perspective.Protein pocket and ligand shape comparison and its application in virtual screening.Heterodimer Binding Scaffolds Recognition via the Analysis of Kinetically Hot Residues.2P2Ichem: focused chemical libraries dedicated to orthosteric modulation of protein–protein interactionsSynthesis and Pharmacological Evaluation of α4β2Nicotinic Ligands with a 3-Fluoropyrrolidine Nucleus
P2860
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P2860
Ligand efficiency indices for an effective mapping of chemico-biological space: the concept of an atlas-like representation.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Ligand efficiency indices for ...... an atlas-like representation.
@en
Ligand efficiency indices for ...... an atlas-like representation.
@nl
type
label
Ligand efficiency indices for ...... an atlas-like representation.
@en
Ligand efficiency indices for ...... an atlas-like representation.
@nl
prefLabel
Ligand efficiency indices for ...... an atlas-like representation.
@en
Ligand efficiency indices for ...... an atlas-like representation.
@nl
P2093
P50
P1433
P1476
Ligand efficiency indices for ...... f an atlas-like representation
@en
P2093
A Patrícia Bento
Cele Abad-Zapatero
Michael E Johnson
P304
P356
10.1016/J.DRUDIS.2010.08.004
P577
2010-08-19T00:00:00Z