about
Critical contribution of aromatic rings to specific recognition of polyether rings. The case of ciguatoxin CTX3C-ABC and its specific antibody 1C49Allosteric regulation of epoxide opening cascades by a pair of epoxide hydrolases in monensin biosynthesisParallel and four-step synthesis of natural-product-inspired scaffolds through modular assembly and divergent cyclization.Phage-display selection of antibodies to the left end of CTX3C using synthetic fragments.Complete sequence of biosynthetic gene cluster responsible for producing triostin A and evaluation of quinomycin-type antibiotics from Streptomyces triostinicus.Diversification of echinomycin molecular structure by way of chemoenzymatic synthesis and heterologous expression of the engineered echinomycin biosynthetic pathway.Total synthesis of ciguatoxin CTX3C.Total biosynthesis of antitumor nonribosomal peptides in Escherichia coli.Solanapyrone synthase, a possible Diels-Alderase and iterative type I polyketide synthase encoded in a biosynthetic gene cluster from Alternaria solani.Rationally engineered total biosynthesis of a synthetic analogue of a natural quinomycin depsipeptide in Escherichia coli.Pictet-Spenglerase involved in tetrahydroisoquinoline antibiotic biosynthesis.Biosynthetic machinery of ionophore polyether lasalocid: enzymatic construction of polyether skeleton.Involvement of common intermediate 3-hydroxy-L-kynurenine in chromophore biosynthesis of quinomycin family antibiotics.An anti-tetraamination of a 1,3-diene unit via cascade annulations of the azulenone scaffold with dicarbonyl azo-compounds.Intriguing substrate tolerance of epoxide hydrolase Lsd19 involved in biosynthesis of the ionophore antibiotic lasalocid A.Concise synthesis of ciguatoxin ABC-ring fragments and surface plasmon resonance study of the interaction of their BSA conjugates with monoclonal antibodies.Synthesis-based approach toward direct sandwich immunoassay for ciguatoxin CTX3C.Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.Enzymatic macrolactonization in the presence of DNA leading to triostin A analogs.Relative and absolute configuration of antitumor agent SW-163D.Core assembly mechanism of quinocarcin/SF-1739: bimodular complex nonribosomal peptide synthetases for sequential mannich-type reactions.Biogenetically inspired synthesis and skeletal diversification of indole alkaloids.Divergent and expeditious access to fused skeletons inspired by indole alkaloids and transtaganolides.The Pictet-Spengler mechanism involved in the biosynthesis of tetrahydroisoquinoline antitumor antibiotics: a novel function for a nonribosomal peptide synthetase.Reconstruction of the saframycin core scaffold defines dual Pictet-Spengler mechanisms.Bioorganic Studies Utilizing Rationally Designed Synthetic Molecules: Absolute Configuration of Ciguatoxin and Development of Immunoassay SystemsSynthesis of the fully functionalized ABCDE ring moiety of ciguatoxinConstruction of the benzylic quaternary carbon center of zoanthenol by intramolecular Mizoroki-Heck reaction of enoneIdentification and stereochemical assignment of the beta-hydroxytryptophan intermediate in the echinomycin biosynthetic pathwaySkeletal diversity via a folding pathway: synthesis of indole alkaloid-like skeletonsEnantioselective synthesis of the fully functionalized ABC ring of zoanthenolSkeletal and stereochemical diversification of tricyclic frameworks inspired by Ca(2+)-ATPase inhibitors, artemisinin and transtaganolide DEnzymatic epoxide-opening cascades catalyzed by a pair of epoxide hydrolases in the ionophore polyether biosynthesisSequential enzymatic epoxidation involved in polyether lasalocid biosynthesisHg(OTf)(2)-catalyzed direct vinylation of tryptamines and versatile applications for tandem reactionsSequential [6+2], [2+2], and [3+2] annulations for rapid assembly of multiple fragmentsHeterologous expression of highly reducing polyketide synthase involved in betaenone biosynthesisNickel-catalyzed dimerization of pyrrolidinoindoline scaffolds: systematic access to chimonanthines, folicanthines and (+)-WIN 64821Biomimetic Assembly Lines Producing Natural Product Analogs: Strategies from a Versatile Manifold to Skeletally Diverse ScaffoldsSynthesis of multiply substituted 1,6-dihydropyridines through Cu(I)-catalyzed 6-endo cyclization
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Hiroki Oguri
@ast
Hiroki Oguri
@en
Hiroki Oguri
@es
Hiroki Oguri
@nl
Hiroki Oguri
@sl
type
label
Hiroki Oguri
@ast
Hiroki Oguri
@en
Hiroki Oguri
@es
Hiroki Oguri
@nl
Hiroki Oguri
@sl
prefLabel
Hiroki Oguri
@ast
Hiroki Oguri
@en
Hiroki Oguri
@es
Hiroki Oguri
@nl
Hiroki Oguri
@sl
P1053
F-9541-2015
P106
P21
P31
P3829
P496
0000-0001-8007-1631
P569
2000-01-01T00:00:00Z