A conserved gammaherpesvirus protein kinase targets histone deacetylases 1 and 2 to facilitate viral replication in primary macrophages.
about
A locus encompassing the Epstein-Barr virus bglf4 kinase regulates expression of genes encoding viral structural proteinsProteomic characterization of murid herpesvirus 4 extracellular virionsHuman cytomegalovirus pUL97 regulates the viral major immediate early promoter by phosphorylation-mediated disruption of histone deacetylase 1 binding.Hsp90 inhibitor 17-DMAG decreases expression of conserved herpesvirus protein kinases and reduces virus production in Epstein-Barr virus-infected cellsInfluenza A Virus Dysregulates Host Histone Deacetylase 1 That Inhibits Viral Infection in Lung Epithelial CellsPrimary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection.Histone H3K14 hypoacetylation and H3K27 hypermethylation along with HDAC1 up-regulation and KDM6B down-regulation are associated with active pulmonary tuberculosis diseaseDirect Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk).
P2860
Q34105467-19480D74-F016-45FC-BDEB-1BA019DA8219Q35080693-ECBBB59D-ABDA-4FDE-B73D-9E6EA6BFC262Q36978826-B07F8FAD-9440-45A3-9E3D-27A5BCE47B4EQ37123188-6698472D-416A-45A2-99FD-7974E9BFB0C6Q38791236-1E8B25C0-76FD-488A-9DF1-921A4F4C4DB4Q41908887-A0CB2D27-2157-4B04-ABFC-9242B72A02B0Q42068184-209BD3B7-F74C-4563-8F9E-C4FDD22EFA75Q47319898-2987FAED-BE0F-4671-B25B-D570FD118B74
P2860
A conserved gammaherpesvirus protein kinase targets histone deacetylases 1 and 2 to facilitate viral replication in primary macrophages.
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A conserved gammaherpesvirus p ...... cation in primary macrophages.
@en
A conserved gammaherpesvirus p ...... cation in primary macrophages.
@nl
type
label
A conserved gammaherpesvirus p ...... cation in primary macrophages.
@en
A conserved gammaherpesvirus p ...... cation in primary macrophages.
@nl
prefLabel
A conserved gammaherpesvirus p ...... cation in primary macrophages.
@en
A conserved gammaherpesvirus p ...... cation in primary macrophages.
@nl
P2093
P2860
P356
P1433
P1476
A conserved gammaherpesvirus p ...... cation in primary macrophages.
@en
P2093
Scott S Terhune
Tarin M Bigley
Vera L Tarakanova
Wadzanai P Mboko
P2860
P304
P356
10.1128/JVI.02713-12
P407
P577
2013-04-24T00:00:00Z